Immunemodulation in Patients With Minor Head Injury

NCT ID: NCT00622778

Last Updated: 2012-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

130 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-10-31

Study Completion Date

2011-07-31

Brief Summary

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The purpose of this study is to try to prove the worth of the two (2) Serum Proteins S-100 Beta and NSE in combination with a diagnostic algorithm to help to establish diagnosis in patients with minor head injury.

Detailed Description

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Conditions

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Head Trauma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Patients from daily practice

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* minor head injury

Exclusion Criteria

* severe head injury
Minimum Eligible Age

1 Year

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Vienna

OTHER

Sponsor Role lead

Responsible Party

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Department for Trauma Surgery

Principal Investigators

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Vilmos Vecsei, M.D. Professor

Role: STUDY_CHAIR

Head of Department

Locations

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Medical University of Vienna

Vienna, Vienna, Austria

Site Status

Countries

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Austria

References

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Pelinka LE, Toegel E, Mauritz W, Redl H. Serum S 100 B: a marker of brain damage in traumatic brain injury with and without multiple trauma. Shock. 2003 Mar;19(3):195-200. doi: 10.1097/00024382-200303000-00001.

Reference Type BACKGROUND
PMID: 12630517 (View on PubMed)

Pelinka LE, Bahrami S, Szalay L, Umar F, Redl H. Hemorrhagic shock induces an S 100 B increase associated with shock severity. Shock. 2003 May;19(5):422-6. doi: 10.1097/01.shk.0000055345.58165.52.

Reference Type BACKGROUND
PMID: 12744484 (View on PubMed)

Pelinka LE, Kroepfl A, Leixnering M, Buchinger W, Raabe A, Redl H. GFAP versus S100B in serum after traumatic brain injury: relationship to brain damage and outcome. J Neurotrauma. 2004 Nov;21(11):1553-61. doi: 10.1089/neu.2004.21.1553.

Reference Type BACKGROUND
PMID: 15684648 (View on PubMed)

Wolf H, Frantal S, Pajenda GS, Salameh O, Widhalm H, Hajdu S, Sarahrudi K. Predictive value of neuromarkers supported by a set of clinical criteria in patients with mild traumatic brain injury: S100B protein and neuron-specific enolase on trial: clinical article. J Neurosurg. 2013 Jun;118(6):1298-303. doi: 10.3171/2013.1.JNS121181. Epub 2013 Mar 1.

Reference Type DERIVED
PMID: 23451906 (View on PubMed)

Other Identifiers

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3-Wolf

Identifier Type: -

Identifier Source: org_study_id

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