Trial Outcomes & Findings for The Effect on Cognition of Terminating ECT Induced Seizures With Propofol (NCT NCT00616759)

NCT ID: NCT00616759

Last Updated: 2021-06-08

Results Overview

WMS-III Auditory Delayed Index is a measure of memory functioning. The results given are the post-ECT testing results. A smaller number indicates less memory disturbance on this scale. The range of scores is between 0-140 with higher scores indicating better memory function.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

20 participants

Primary outcome timeframe

Pre-tesing within 36 hours before first ECT; Post-testing within 36 hours of 6th ECT.

Results posted on

2021-06-08

Participant Flow

Participant milestones

Participant milestones
Measure
Series of 6 ECTs Performed With Standard Technique
Electroconvulsive Therapy (ECT) as usual
6 ECTs Where Seizure Was Shortened by Propofol
ECT-induced seizures terminated with propofol
Overall Study
STARTED
10
10
Overall Study
COMPLETED
7
8
Overall Study
NOT COMPLETED
3
2

Reasons for withdrawal

Reasons for withdrawal
Measure
Series of 6 ECTs Performed With Standard Technique
Electroconvulsive Therapy (ECT) as usual
6 ECTs Where Seizure Was Shortened by Propofol
ECT-induced seizures terminated with propofol
Overall Study
Physician Decision
2
0
Overall Study
Withdrawal by Subject
1
2

Baseline Characteristics

The Effect on Cognition of Terminating ECT Induced Seizures With Propofol

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: Pre-tesing within 36 hours before first ECT; Post-testing within 36 hours of 6th ECT.

Population: PI left institution without completing results. Multiple attempts to contact PI have been unsuccessful. No data available to submit.

WMS-III Auditory Delayed Index is a measure of memory functioning. The results given are the post-ECT testing results. A smaller number indicates less memory disturbance on this scale. The range of scores is between 0-140 with higher scores indicating better memory function.

Outcome measures

Outcome data not reported

Adverse Events

Series of 6 ECTs Performed With Standard Technique

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

6 ECTs Where Seizure Was Shortened by Propofol

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Ronald L. Warnell, M.D.

Loma Linda University

Phone: 909-558-9551

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place