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Practice Structure on Motor Learning in Post-Stroke Patients

NCT ID: NCT00604747

Last Updated: 2008-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-08-31

Study Completion Date

2007-07-31

Brief Summary

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Background: The literature indicates that, in relation to motor learning, healthy subjects benefit more from random practice than from constant practice. However, this effect is not well known in post-stroke patients. Objective: The goal of this study was to investigate the effects of practice structure on motor learning in post-stroke patients. Methods: Participants included an experimental group (EG) of post-stroke patients: 17 males and females; and a control group (CG) of healthy individuals: 17 males and females. At the acquisition phase, all participants performed 30 trials of a coincident timing task. Nine individuals from each group practiced constantly (C) at a stimulus propagation speed of 3 mph, and eight from each group practiced randomly (R) at speeds of 2, 3, and 5 mph. Subsequent phases included: 1) transfer, 2) retention after 15 minutes, and 3) retention after 3 days. Each of these phases included 20 trials: 10 at a speed of 1 mph, and 10 at a speed of 4 mph. Intra- and inter-group comparisons were made employing an alpha level of 0.05 (5%).

Detailed Description

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Utilized was Bassin's anticipation timer (Lafayette Instruments #50575), which is comprised of a control screen, one 1.52 m gutter with 32 diodes placed on it linearly, and a response button. The screen has a digital display, with commands that permit the operator to control the stimulus propagation speed and the preparatory interval speed. Once activated, the screen exhibits an alert signal, and, after the preparatory interval, it initiates the propagation of a luminous stimulus, lighting the 32 diodes successively. The task required participants to press the response button simultaneously with the illumination of the last diode. The digital display showed the error measure (em): that is, the difference between the illumination of the last diode and the response.

Conditions

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Stroke

Keywords

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motor learning hemiplegia stroke practice physiotherapy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1, 2

Group Type OTHER

Structure practice

Intervention Type OTHER

there were 2 groups which received random practice and constant practice during acquisition phase

Interventions

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Structure practice

there were 2 groups which received random practice and constant practice during acquisition phase

Intervention Type OTHER

Other Intervention Names

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experimental group (EG) control group (CG)

Eligibility Criteria

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Inclusion Criteria

1. First cerebrovascular accident
2. Lesion covering the middle and the anterior cerebral artery territories
3. Presence of hemiplegia or hemiparesis
4. Mini-Mental State Examination (MMSE) score above 24 (19)
5. Sufficient attention and comprehension to perform the task
6. Absence of other associated neurological diseases.

Exclusion Criteria

1. Acute medical problems
2. Uncorrected vision loss
3. Previous history of psychiatric admission
4. History of multiple strokes, transient ischemic attacks
5. Pathology of the less affected, ipsilateral to stroke upper extremity that would affect ability to perform the task
6. Score of 23 or less on the MMSE
7. Difficulty in comprehension of verbal command and simple instructions
8. Aphasia of comprehension.
Minimum Eligible Age

40 Years

Maximum Eligible Age

62 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Sao Paulo

OTHER

Sponsor Role lead

Responsible Party

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University of São Paulo

Principal Investigators

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Camila Torriani

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Camila Torriani

Role: STUDY_CHAIR

University of Sao Paulo

Locations

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Camila Torriani

São Paulo, São Paulo, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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0038.0.254.000-05

Identifier Type: -

Identifier Source: secondary_id

0038.0.254.000-05

Identifier Type: -

Identifier Source: org_study_id