Trial Outcomes & Findings for Venovenous CO2 Removal (VVCO2R) in Patients With COPD and Acute Respiratory Failure (NCT NCT00594009)

NCT ID: NCT00594009

Last Updated: 2019-03-12

Results Overview

The amount of CO2 removed in cc/min will be recorded. The level of blood flow (ml/min) and gas flow (l/min) at each measurement of CO2 removal will also be recorded

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

1 participants

Primary outcome timeframe

0 to 96 hours

Results posted on

2019-03-12

Participant Flow

Participant milestones

Participant milestones
Measure
Venovenous CO2 Removal (VVCO2R) in COPD
All patients enrolled in the trial will receive the proposed Patients who meet criteria will be placed on an extracorporeal device for CO2 removal for up to 96 hours for treatment of COPD exacerbation requiring hospitalization and intensive care
Overall Study
STARTED
1
Overall Study
COMPLETED
1
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Venovenous CO2 Removal (VVCO2R) in Patients With COPD and Acute Respiratory Failure

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
VVCO2R in COPD
n=1 Participants
All patients enrolled in the trial will receive the proposed intervention Rotaflow centrifugal pump (Maquet, Inc.): Patients who meet criteria will be placed on an extracorporeal device for CO2 removal for up to 96 hours for treatment of COPD exacerbation requiring hospitalization and intensive care
Age, Continuous
42 years
STANDARD_DEVIATION NA • n=5 Participants
Sex: Female, Male
Female
1 Participants
n=5 Participants
Sex: Female, Male
Male
0 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
0 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
1 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=5 Participants
Race (NIH/OMB)
White
1 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Region of Enrollment
United States
1 participants
n=5 Participants
chronic obstructive pulmonary disease (COPD) patients
1 Participants
n=5 Participants

PRIMARY outcome

Timeframe: 0 to 96 hours

The amount of CO2 removed in cc/min will be recorded. The level of blood flow (ml/min) and gas flow (l/min) at each measurement of CO2 removal will also be recorded

Outcome measures

Outcome measures
Measure
VVCO2R in COPD
n=1 Participants
All patients enrolled in the trial will receive the proposed intervention Patients who meet criteria will be placed on an extracorporeal device for CO2 removal for up to 96 hours for treatment of COPD exacerbation requiring hospitalization and intensive care
The Amount of CO2 Transferred Through the Oxygenator at Various Levels of Blood and Gas Flow
75 cc/min

Adverse Events

VVCO2R in COPD

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Victor Cardenas, MD

University of Texas Medical Branch

Phone: (409) 772-2436

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place