Trial Outcomes & Findings for Treatment of Language and Memory in Patients With Alzheimer's Disease (NCT NCT00593372)

NCT ID: NCT00593372

Last Updated: 2017-01-09

Results Overview

Successful memory tasks are those memory tasks (such as "where do I keep my keys") that participants are able to consistently respond to.

• Recruitment status: COMPLETED
• Study phase: PHASE1
• Target enrollment: 11 participants
• Primary outcome timeframe: 8 weeks
• Results posted on: 2017-01-09

Participant Flow

Participant milestones

Measure	Spaced Retrieval Therapy Participants continue on current medication but participate in spaced retrieval memory training, as well.	Continuing Medication Only Participants continue on current medication and are assessed at beginning and end of study duration.
Overall Study STARTED	8	3
Overall Study COMPLETED	8	3
Overall Study NOT COMPLETED	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Treatment of Language and Memory in Patients With Alzheimer's Disease

Baseline characteristics by cohort

Measure	Spaced Retrieval Therapy n=8 Participants Participants continue on current medication but participate in spaced retrieval memory training, as well.	Continuing Medication Only n=3 Participants Participants continue on current medication and are assessed at beginning and end of study duration.	Total n=11 Participants Total of all reporting groups
Age, Categorical <=18 years	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Age, Categorical Between 18 and 65 years	1 Participants n=5 Participants	0 Participants n=7 Participants	1 Participants n=5 Participants
Age, Categorical >=65 years	7 Participants n=5 Participants	3 Participants n=7 Participants	10 Participants n=5 Participants
Age, Continuous	74 years STANDARD_DEVIATION 5 • n=5 Participants	72 years STANDARD_DEVIATION 3 • n=7 Participants	72 years STANDARD_DEVIATION 6 • n=5 Participants
Gender Female	2 Participants n=5 Participants	2 Participants n=7 Participants	4 Participants n=5 Participants
Gender Male	6 Participants n=5 Participants	1 Participants n=7 Participants	7 Participants n=5 Participants
Region of Enrollment United States	8 participants n=5 Participants	3 participants n=7 Participants	11 participants n=5 Participants

PRIMARY outcome

Timeframe: 8 weeks

Successful memory tasks are those memory tasks (such as "where do I keep my keys") that participants are able to consistently respond to.

Outcome measures

Measure	Spaced Retrieval Therapy n=8 Participants Participants continue on current medication but participate in spaced retrieval memory training, as well.	Continuing Medication Only n=3 Participants Participants continue on current medication and are assessed at beginning and end of study duration.
Number of Successful Memory Tasks Completed Over Study Period.	5 memory tasks	0 memory tasks

SECONDARY outcome

Timeframe: End of Study

Outcome measures

Outcome data not reported

Adverse Events

Spaced Retrieval Therapy

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Continuing Medication Only

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Gary McCullough

UAMS Medical Center

Phone: 501-852-7886

Email: garyhmccullough@uams.edu

Results disclosure agreements

• Principal investigator is a sponsor employee
• Publication restrictions are in place