Efficacy and Safety Study of Bepotastine Besilate Ophthalmic Solution in Allergic Conjunctivitis

NCT ID: NCT00586664

Last Updated: 2013-02-08

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

130 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-10-31

Study Completion Date

2008-06-30

Brief Summary

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Efficacy and safety study of bepotastine besilate ophthalmic solution in allergic conjunctivitis

Detailed Description

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Conditions

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Allergic Conjunctivitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Bepreve (Bepotastine Besilate Ophthalmic Solution) 1.5%

Group Type EXPERIMENTAL

Bepreve (bepotastine besilate ophthalmic solution) 1.5%

Intervention Type DRUG

sterile ophthalmic solution

Bepotastine Besilate Ophthalmic Solution 1.0%

Group Type EXPERIMENTAL

Bepotastine Besilate Ophthalmic Solution 1.0%

Intervention Type DRUG

sterile ophthalmic solution

Placebo

Group Type PLACEBO_COMPARATOR

placebo comparator

Intervention Type DRUG

sterile ophthalmic solution

Interventions

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Bepreve (bepotastine besilate ophthalmic solution) 1.5%

sterile ophthalmic solution

Intervention Type DRUG

placebo comparator

sterile ophthalmic solution

Intervention Type DRUG

Bepotastine Besilate Ophthalmic Solution 1.0%

sterile ophthalmic solution

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Subjects must be at least 10 years of age

Exclusion Criteria

* No active ocular disease
Minimum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bausch & Lomb Incorporated

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tim McNamara, PharmD

Role: STUDY_DIRECTOR

ISTA Pharmaceuticals, Inc.

Locations

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ISTA Pharmaceuticals, Inc.

Irvine, California, United States

Site Status

Countries

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United States

References

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Meier EJ, Torkildsen GL, Gow JA, McNamara TR, Gomes PJ, Williams JI; Bepotastine Besilate Ophthalmic Solutions Study Group. Integrated phase III trials of bepotastine besilate ophthalmic solution 1.5% for ocular itching associated with allergic conjunctivitis. Allergy Asthma Proc. 2012 May-Jun;33(3):265-74. doi: 10.2500/aap.2012.33.3570.

Reference Type DERIVED
PMID: 22991696 (View on PubMed)

Macejko TT, Bergmann MT, Williams JI, Gow JA, Gomes PJ, McNamara TR, Abelson MB; Bepotastine Besilate Ophthalmic Solutions Clinical Study Group. Multicenter clinical evaluation of bepotastine besilate ophthalmic solutions 1.0% and 1.5% to treat allergic conjunctivitis. Am J Ophthalmol. 2010 Jul;150(1):122-127.e5. doi: 10.1016/j.ajo.2010.02.007. Epub 2010 May 20.

Reference Type DERIVED
PMID: 20488431 (View on PubMed)

Other Identifiers

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CL-S&E-0409071-P

Identifier Type: -

Identifier Source: org_study_id

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