Trial Outcomes & Findings for Endovascular Exclusion of TAAA/AAA Utilizing Fenestrated/Branched Stent Grafts (NCT NCT00583050)

NCT ID: NCT00583050

Last Updated: 2020-05-08

Results Overview

Absence of blood extravasation outside of aneurysm sac demonstrated by CT scan

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

1366 participants

Primary outcome timeframe

2 years

Results posted on

2020-05-08

Participant Flow

Participant milestones

Participant milestones
Measure
Endovascular Aneurysm Repair
Treatment Arm: Subjects with abdominal/thoracoabdominal aneurysm undergoing endovascular aneurysm repair
Overall Study
STARTED
1366
Overall Study
COMPLETED
1366
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Endovascular Aneurysm Repair
n=1366 Participants
Treatment Arm: Subjects with abdominal/thoracoabdominal aneurysm undergoing endovascular aneurysm repair
Age, Categorical
<=18 years
0 Participants
n=1366 Participants
Age, Categorical
Between 18 and 65 years
141 Participants
n=1366 Participants
Age, Categorical
>=65 years
1225 Participants
n=1366 Participants
Sex: Female, Male
Female
315 Participants
n=1366 Participants
Sex: Female, Male
Male
1051 Participants
n=1366 Participants
Region of Enrollment
United States
1366 participants
n=1366 Participants
Presence of abdominal or thoracoabdominal aneurysm
1366 Participants
n=1366 Participants

PRIMARY outcome

Timeframe: 2 years

Absence of blood extravasation outside of aneurysm sac demonstrated by CT scan

Outcome measures

Outcome measures
Measure
Endovascular Aneurysm Repair
n=1366 Participants
Treatment Arm: Subjects with abdominal/thoracoabdominal aneurysm undergoing endovascular aneurysm repair
Freedom From Aneurysm Rupture
22 Participants

Adverse Events

Endovascular Aneurysm Repair

Serious events: 22 serious events
Other events: 68 other events
Deaths: 775 deaths

Serious adverse events

Serious adverse events
Measure
Endovascular Aneurysm Repair
n=1366 participants at risk
Treatment Arm: Subjects with abdominal/thoracoabdominal aneurysm undergoing endovascular aneurysm repair
Vascular disorders
Aneurysm Rupture
1.6%
22/1366 • 2 years

Other adverse events

Other adverse events
Measure
Endovascular Aneurysm Repair
n=1366 participants at risk
Treatment Arm: Subjects with abdominal/thoracoabdominal aneurysm undergoing endovascular aneurysm repair
Vascular disorders
Aneurysm size increase
5.0%
68/1366 • 2 years

Additional Information

Matthew Eagleton, M. D.

Massachusetts General Hospital

Phone: 617-726-8279

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place