The Effect of Rehabilitation for Patients Living With an Implantable Cardioverter Defibrillator

NCT ID: NCT00569478

Last Updated: 2012-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

196 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-10-31

Study Completion Date

2011-10-31

Brief Summary

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The purpose of this study is to describe the effect and meaning of an outpatient-nursing programme including physical activity for patients with implantable cardioverter defibrillators (ICD).

Hypothesis: The outpatient nursing programme will increase the perceived health and quality of life; improve the management of life from a patient perspective; reduce fear of exercise and increase physical capability and reduce the number of treatment-demanding arrhythmias.

Detailed Description

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Implantable cardioverter defibrillators (ICD) are used in the treatment of life-threatening heart arrhythmia and the prevention of sudden cardiac death (SCD). The ICD terminates arrhythmia by delivering therapy in the form of electrical impulses to the heart. Patients have described the high energy shock administered by the devise as feeling like a painful kick in the chest.

Patients, who receive an ICD are very much protected against SCD and it is assumed that they are less worried and effected by their heart disease than others. That is not correct though. Studies have shown, that living with an ICD can lead to anxiety, fear of shock and avoidance of situations, places and objects that are associated to shock. It often leads to social isolation, avoidance of physical activity and mood-disturbances.

The purpose of this study is to describe the effect and meaning of an outpatient-nursing programme including physical activity for patients with ICD.

Hypothesis: see above

Intervention: The outpatient nursing programme has a duration of 1 year and is directed towards parameters that ICD reportedly affect. The focus is prevention of the known risks and problems. The content is partly information and education in managing an ICD, partly emotional reactions and further discussion of handling life with ICD. 3-month into the program physical training lead by a physical therapist is started. It is optimal whether to carry out the twice-weekly physical training program at home or at the hospital.

180 patients, who get an ICD transplanted at Copenhagen university Hospital, Rigshospitalet, are included in the study prior to discharge. 90 patients in the intervention group and 90 controls.

Using questionnaires, qualitative interviews, work-test, 6 MWT and decoding ICD the effect and meaning of the programme is evaluated.

Conditions

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Quality of Life

Keywords

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ICD Rehabilitation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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1

rehabilitation

Group Type ACTIVE_COMPARATOR

rehabilitation

Intervention Type OTHER

Nursing consultations and physical training

2

controls

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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rehabilitation

Nursing consultations and physical training

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* In-patients at Copenhagen University Hospital who just received an ICD for the first time.

Exclusion Criteria

* Patients who:

* do not understand the instructions,
* are under 18 years old,
* are diagnosed with a mental disease,
* suffer from a competing disease,
* can not participate in physical training.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Novo Nordisk A/S

INDUSTRY

Sponsor Role collaborator

Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Selina Kikkenborg Berg

Ph.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Selina K Berg, PhD Fellow

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Jesper H Svendsen

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Preben U Pedersen

Role: PRINCIPAL_INVESTIGATOR

Aarhus Universitet

Birthe D Pedersen

Role: PRINCIPAL_INVESTIGATOR

Aarhus Universitet

Locations

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Rigshospitalet

Copenhagen, , Denmark

Site Status

Countries

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Denmark

References

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Berg SK, Moons P, Zwisler AD, Winkel P, Pedersen BD, Pedersen PU, Svendsen JH. Phantom shocks in patients with implantable cardioverter defibrillator: results from a randomized rehabilitation trial (COPE-ICD). Europace. 2013 Oct;15(10):1463-7. doi: 10.1093/europace/eut087. Epub 2013 Apr 18.

Reference Type DERIVED
PMID: 23599170 (View on PubMed)

Berg SK, Svendsen JH, Zwisler AD, Pedersen BD, Preisler P, Siersbaek-Hansen L, Hansen MB, Nielsen RH, Pedersen PU. COPE-ICD: a randomised clinical trial studying the effects and meaning of a comprehensive rehabilitation programme for ICD recipients -design, intervention and population. BMC Cardiovasc Disord. 2011 Jun 17;11:33. doi: 10.1186/1471-2261-11-33.

Reference Type DERIVED
PMID: 21682864 (View on PubMed)

Other Identifiers

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1-Berg

Identifier Type: -

Identifier Source: org_study_id