Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Advanced or Metastatic Solid Tumors
NCT ID: NCT00569036
Last Updated: 2013-08-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
63 participants
INTERVENTIONAL
2008-04-30
2013-04-30
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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BMS-754807
Single arm, multiple-ascending dose escalation study
BMS-754807
Tablets, Oral, Dose Cohorts: 4mg, 10mg, 20mg, 30mg, 50mg, 70mg, 100mg, 130mg, 160mg, 200mg, Once Daily, Until disease progression, unacceptable toxicity or at the subject's request
Interventions
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BMS-754807
Tablets, Oral, Dose Cohorts: 4mg, 10mg, 20mg, 30mg, 50mg, 70mg, 100mg, 130mg, 160mg, 200mg, Once Daily, Until disease progression, unacceptable toxicity or at the subject's request
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* ECOG performance status 0-1
* at least 4 weeks between surgery or last dose prior anti-cancer therapy
Exclusion Criteria
* any disorder or dysregulation of glucose homeostasis {e.g. diabetes)
* uncontrolled or significant cardiovascular disease
* inadequate bone marrow, liver or kidney function
18 Years
ALL
No
Sponsors
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Bristol-Myers Squibb
INDUSTRY
Responsible Party
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Principal Investigators
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Bristol-Myers Squibb
Role: STUDY_DIRECTOR
Bristol-Myers Squibb
Locations
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Local Institution
East Melbourne, Victoria, Australia
Local Institution
Footscray, Victoria, Australia
Local Institution
Heidelberg, Victoria, Australia
Local Institution
Parkville, Victoria, Australia
Local Institution
Nedlands, Western Australia, Australia
Countries
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Related Links
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Investigator Inquiry form
Other Identifiers
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CA191-002
Identifier Type: -
Identifier Source: org_study_id