A Study to Investigate the Influence of MK0859 on Blood Pressure (MK-0859-012)(COMPLETED)
NCT ID: NCT00565006
Last Updated: 2015-02-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
22 participants
INTERVENTIONAL
2006-07-31
2006-09-30
Brief Summary
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Detailed Description
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Conditions
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Interventions
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MK0859
Eligibility Criteria
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Inclusion Criteria
* You are a man or non-pregnant woman
* You agree to not eat or drink fruit or fruit juices (orange, apple or grapefruit) for 2 weeks before starting study medication
Exclusion Criteria
* You have used St. John's Wort or any products that include it within the last 2 weeks
* You have used herbal, organic, dietary or nutritional remedies within the last 2 weeks
* You have a history of drug allergies (anaphylaxis, angioedema)
* You have taken an investigational drug in another clinical trial within the last 4 weeks
* You have a history of cardiovascular disease including hypertension (high blood pressure)
* You have a history of renal disease
* You have a history of gall bladder disease or have had abnormal liver function tests
* You have a history of drug or alcohol abuse
* You drink more than 6 cups of caffeinated beverages a day (coffee, tea or cola)
45 Years
75 Years
ALL
Yes
Sponsors
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Merck Sharp & Dohme LLC
INDUSTRY
Responsible Party
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Principal Investigators
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Medical Monitor
Role: STUDY_DIRECTOR
Merck Sharp & Dohme LLC
References
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Krishna R, Anderson MS, Bergman AJ, Jin B, Fallon M, Cote J, Rosko K, Chavez-Eng C, Lutz R, Bloomfield DM, Gutierrez M, Doherty J, Bieberdorf F, Chodakewitz J, Gottesdiener KM, Wagner JA. Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studies. Lancet. 2007 Dec 8;370(9603):1907-14. doi: 10.1016/S0140-6736(07)61813-3.
Other Identifiers
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2007_656
Identifier Type: -
Identifier Source: secondary_id
0859-012
Identifier Type: -
Identifier Source: org_study_id
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