Delayed Umbilical Cord Clamping in Infants Less Than 32 Weeks
NCT ID: NCT00562536
Last Updated: 2007-11-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
296 participants
INTERVENTIONAL
2007-11-30
2010-11-30
Brief Summary
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Our specific aim is to determine if a 30 to 45 second delay in umbilical cord clamping improves neonatal outcome as assessed by a composite of intraventricular hemorrhage and late onset sepsis in preterm infants born between 24 and 32 weeks gestation. Secondary outcomes to be examined include improvements in the following: 1) lung function as assessed by oxygen dependency at 36 weeks corrected gestational age (CGA), 2) cardiovascular function as assessed by the need for volume expansion, inotropes, or clinically suspected PDA requiring intervention prior to discharge home, and 3) anemia as assessed by initial hemoglobin, need for transfusion during stay in the NICU, and number of transfusions.
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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A 1
Delayed umbilical cord clamping 30-45 seconds.
Umbilical cord clamping
Delay of umbilical cord clamping 30 to 45 seconds
A 2
Immediate umbilibcal cord clamping
No interventions assigned to this group
Interventions
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Umbilical cord clamping
Delay of umbilical cord clamping 30 to 45 seconds
Eligibility Criteria
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Inclusion Criteria
* Singleton pregnancy (Note: if pregnancy was a multiple gestation but demised occurred prior to 13 weeks, these patients can be included in study).
Exclusion Criteria
* Multiple live gestations at birth (e.g. twins, triplets, etc)
* Intrauterine fetal demise
* Previous participation
* Stem cell collection
15 Years
50 Years
FEMALE
Yes
Sponsors
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Mount Sinai Hospital, Canada
OTHER
Principal Investigators
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Kellie E Murphy, MD MSc
Role: PRINCIPAL_INVESTIGATOR
Mount Sinai Hospital, Canada
Locations
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Mount Sinai Hospital
Toronto, Ontario, Canada
Countries
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Central Contacts
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Facility Contacts
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Kellie E. Murphy, MD MSc
Role: primary
References
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Chu KS, Shah PS, Whittle WL, Windrim R, Murphy KE. The "DUC" trial: a pilot randomized controlled trial of immediate versus delayed cord clamping in preterm infants born between 24 and 32 weeks gestation. J Matern Fetal Neonatal Med. 2021 Dec;34(24):4049-4052. doi: 10.1080/14767058.2019.1702959. Epub 2019 Dec 25.
Other Identifiers
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Mount Sinai Hospital Toronto
Identifier Type: -
Identifier Source: org_study_id