Efficacy Study of Intramuscular or Intracoronary Injection of Autologous Bone Marrow Cells to Treat Scarred Myocardium
NCT ID: NCT00560742
Last Updated: 2007-11-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
63 participants
INTERVENTIONAL
2002-11-30
2007-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Control
Control
Coronary artery bypass grafting without bone marrow cells injection
Intramuscular
Intramuscular administration of bone marrow cells
Coronary artery bypass grafting, and intramuscular administration of bone marrow cells into myocardial scar
Intracoronary
Intracoronary administration of bone marrow cells
Coronary artery bypass grafting, and intracoronary administration of bone marrow cells into myocardial scar
Interventions
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Control
Coronary artery bypass grafting without bone marrow cells injection
Intramuscular administration of bone marrow cells
Coronary artery bypass grafting, and intramuscular administration of bone marrow cells into myocardial scar
Intracoronary administration of bone marrow cells
Coronary artery bypass grafting, and intracoronary administration of bone marrow cells into myocardial scar
Eligibility Criteria
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Inclusion Criteria
* chronic irreversible myocardial scar
* coronary vessel supplying the scar must be amenable to bypass grafting
Exclusion Criteria
* major organ failures, eg. heart, liver, renal etc
* pre-existing bone marrow conditions
18 Years
ALL
No
Sponsors
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British Heart Foundation
OTHER
University Hospitals, Leicester
OTHER
Principal Investigators
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Manuel Galiñanes, MD PhD FRCS
Role: PRINCIPAL_INVESTIGATOR
University Hospitals, Leicester
Locations
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University Hospitals Leicester
Leicester, Leicestershire, United Kingdom
Countries
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Other Identifiers
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UHL ref: 7638
Identifier Type: -
Identifier Source: secondary_id
PG04050
Identifier Type: -
Identifier Source: org_study_id