Treatment of Carpal Tunnel Syndrome With Dynamic Splinting

NCT ID: NCT00558116

Last Updated: 2008-05-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-05-31

Study Completion Date

2008-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The Purpose of this study is to examine the effect of using the Carpal Tunnel Dynasplint® System on patients diagnosed with CTS in a randomized, controlled, cross-over study.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This study will compare the efficacy of treating Carpal tunnel Syndrome with the Dynasplint® Systems device as compared to a non-treatment control group utilizing a randomized, controlled, cross-over study design. The dependant variables in this study are each patient's score on a Levine-Katz disability and pain scale test, and the change in nerve conduction of the median nerve that was tested upon diagnosis. The independent variables will include three different patient groups separated by randomization. The first group of subjects (selected randomly) will be fit with a therapeutic, functional Carpal Tunnel Dynasplint® versus the second, control patients will not be treated with dynamic splinting for the first sixty (60) days. After the initial sixty (60) days, the original control patients will be fit with a functional Carpal Tunnel Dynasplint® system and this will allow examiner to evaluate for further variance between subject groups, allowing the third group to be a Cross-Over group.

The METHODS for this multi-centered study include recruiting patients from multiple hand surgeons and neurologists and these patients will have been diagnosed with following the physicians' physical examination and a nerve conduction test of the median nerve. The subjects then will be briefed on this study and sign an informed consent as required by the IRB before participating. Subjects who do consent will then be given the Levine-Katz disability and pain scale test, and prior to being fit with the Carpal Tunnel Dynasplint® Subjects will be taught how to use a Carpal Tunnel Dynasplint® properly and after being fit with the Carpal Tunnel Dynasplint® each subject will be required to complete a weekly report showing compliance to the wearing and treatment schedule, and they must attend regular, monthly examinations by the referring physician. After the initial sixty (60) days in the study each subject will repeat the three lead conduction test of the median nerve.

Control subjects at this point will be fit with the Carpal Tunnel Dynasplint® systems becoming Cross-Over subjects and their final nerve conduction test will be administered after they have worn the Carpal Tunnel Dynasplint® system for sixty (60) days. Upon discharge from this study all subjects will also retake the Levine-Katz disability and pain scale test.

Eighty (80) SUBJECTS will be recruited following diagnosis of CTS (using nerve conduction testing of the median nerve for differential diagnosis) and group assignment will be determined through randomization following each patient's completion of the informed consent required by the IRB. All patients randomly selected to start in the experimental group will be fit with functional Carpal Tunnel Dynasplint® and the control group subjects will not be fit until after sixty (60) days. When they are ultimately fit, they will then be categorized as "Cross-Over" subjects to measure continued variance between all groups.

The DURATION for patients enrolled in this study will be sixty (60) days for the experimental subjects and the control subjects will spend their first sixty (60) days as a control role without treatment. However, following sixty days the initial control subjects but then they will be refit with a functional Carpal Tunnel Dynasplint® as a "Cross-Over" subject for an additional sixty (60) days, which makes the control subjects duration in this study 120 days.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Carpal Tunnel Syndrome

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Carpal Tunnel Syndrome Dynamic Splinting Nerve Conduction Studies Splinting Levine Katz Survey

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

1

Treatment with Dynasplint device

Group Type EXPERIMENTAL

Dynamic splinting

Intervention Type DEVICE

The Dynasplint carpal tunnel device will be worn for 30 minutes, twice daily, for 60 consecutive days.

2

Control group; does not receive conservative or surgical treatment.

Group Type NO_INTERVENTION

Dynamic splinting

Intervention Type DEVICE

The Dynasplint carpal tunnel device will be worn for 30 minutes, twice daily, for 60 consecutive days.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Dynamic splinting

The Dynasplint carpal tunnel device will be worn for 30 minutes, twice daily, for 60 consecutive days.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients must exhibit one of the following symptoms of CTS: numbness, tingling, or pain in the wrist or hand
* Patients will be ≥18 years old and of either gender
* Patients will agree and be able to sign a voluntary consent to participate form
* Nerve Conduction study results as follows:

Sensory conduction latency to peak greater than 3.7ms when measured with ring pick up on the volar surface of the index finger measured 14cm from stimulation across the wrist at the median nerve Motor conduction latency to take off greater than 4.2ms when measured with disc pick up on the abductor pollicis brevis muscle measured 8 cm from stimulation across the wrist at the median nerve

\-

Exclusion Criteria

* Patients that have thenar atrophy of the hand
* Patients that are currently undergoing manual, hand therapy
* Patients that have been previously diagnosed with cervical radiculopathy
* Patients whose examination shows evidence of a "Double Crush" syndrome
* Pregnancy
* Nerve Conduction study results as follows:

Sensory conduction latency to peak less than 3.7ms when measured with ring pick up on the volar surface of the index finger measured 14cm from stimulation across the wrist at the median nerve Motor conduction latency to take off less than 4.2ms when measured with disc pick up on the abductor pollicis brevis muscle measured 8cm from stimulation across the wrist at the median nerve
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Dynasplint Systems, Inc.

INDUSTRY

Sponsor Role collaborator

Advanced Centers for Orthopaedic Surgery and Sports Medicine

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Advanced Centers for Orthopaedic Surgery and Sports Medicine

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Stacey H Berner, MD

Role: PRINCIPAL_INVESTIGATOR

Advanced Centers for Orthopaedic Surgery and Sports Medicine

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Advanced Centers for Orthopaedic Surgery and Sports Medicine

Owings Mills, Maryland, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Stacey H Berner, MD

Role: CONTACT

Phone: 410-484-8088

Email: [email protected]

Jacen A Martinez, PA-C

Role: CONTACT

Phone: 410-484-8088

Email: [email protected]

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

101010

Identifier Type: -

Identifier Source: org_study_id