A Safety and Tolerability Study of ABT-089 in Children With Attention-Deficit/Hyperactivity Disorder (ADHD)

NCT ID: NCT00554385

Last Updated: 2011-08-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE2

Total Enrollment

283 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-11-30

Brief Summary

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The objective of this study is to evaluate the long-term safety and tolerability of ABT-089 in children with ADHD.

Detailed Description

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Conditions

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Attention-Deficit/Hyperactivity Disorder

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

Group Type EXPERIMENTAL

ABT-089

Intervention Type DRUG

Up to 4 capsules will be taken once daily for 12 months. Dosage forms include 1 mg, 5 mg, 10 mg capsules and 40 mg tablets. Highest dose allowed is 80 mg per day.

Interventions

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ABT-089

Up to 4 capsules will be taken once daily for 12 months. Dosage forms include 1 mg, 5 mg, 10 mg capsules and 40 mg tablets. Highest dose allowed is 80 mg per day.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* The subject was randomized into Base Study (M06-888 or M10-345) and completed the Treatment Period.
* If female, subject must be practicing at least one method of birth control throughout the study.
* If female, the result of a pregnancy test is negative.
* The subject is judged to be in generally good health.

Exclusion Criteria

* The subject experienced a serious adverse event in Base Study (M06-888 or M10-345) that the investigator considered "possibly" or "probably related" to study drug.
* The subject has taken any ADHD medication between the last dose of study drug in Study M06-888 or M10-345 and the first dose of study drug in the current study.
* The subject has a positive urine drug screen for alcohol or drugs of abuse.
* The subject anticipates a move outside the geographic area.
Minimum Eligible Age

6 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Laura Gault, M.D., Ph.D.

Role: STUDY_DIRECTOR

Abbott

Locations

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Site Ref #/Investigator 6800

Little Rock, Arkansas, United States

Site Status

Site Ref #/Investigator 6812

Boulder, Colorado, United States

Site Status

Site Ref #/Investigator 8366

Bradenton, Florida, United States

Site Status

Site Ref #/Investigator 6808

Jacksonville, Florida, United States

Site Status

Site Ref #/Investigator 6827

Orlando, Florida, United States

Site Status

Site Ref #/Investigator 8383

Libertyville, Illinois, United States

Site Status

Site Ref #/Investigator 6802

Northbrook, Illinois, United States

Site Status

Site Ref #/Investigator 6824

Overland Park, Kansas, United States

Site Status

Site Ref #/Investigator 8428

Troy, Michigan, United States

Site Status

Site Ref #/Investigator 6902

Omaha, Nebraska, United States

Site Status

Site Ref #/Investigator 6856

Las Vegas, Nevada, United States

Site Status

Site Ref #/Investigator 6683

Clementon, New Jersey, United States

Site Status

Site Ref #/Investigator 8297

Oklahoma City, Oklahoma, United States

Site Status

Site Ref #/Investigator 6682

Eugene, Oregon, United States

Site Status

Site Ref #/Investigator 6811

Portland, Oregon, United States

Site Status

Site Ref #/Investigator 8701

Portland, Oregon, United States

Site Status

Site Ref #/Investigator 6681

Salem, Oregon, United States

Site Status

Site Ref #/Investigator 6799

Charleston, South Carolina, United States

Site Status

Site Ref #/Investigator 7955

Memphis, Tennessee, United States

Site Status

Site Ref #/Investigator 6836

Austin, Texas, United States

Site Status

Site Ref #/Investigator 6835

Herndon, Virginia, United States

Site Status

Site Ref #/Investigator 6791

Bellevue, Washington, United States

Site Status

Site Ref #/Investigator 6838

Middleton, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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M10-178

Identifier Type: -

Identifier Source: org_study_id

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