Studying the Preference of Tadalafil to Sildenafil in Men With Problems Getting an Erection Across Nations

NCT ID: NCT00547287

Last Updated: 2007-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

2760 participants

Study Classification

INTERVENTIONAL

Study Start Date

2002-11-30

Study Completion Date

2004-05-31

Brief Summary

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Study to determine if men from around the world prefer sildenafil to tadalafil.

Detailed Description

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Conditions

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Impotence

Study Design

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Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

Currently prescribed dosage of sildenafil is continued until wash-out period.

Group Type ACTIVE_COMPARATOR

sildenafil

Intervention Type DRUG

Current dosage of sildenafil is continued for 4 weeks (no more than once a day) of treatment assessment then the wash-out period will begin.

2

20 mg tadalafil given after one week sildenafil wash-out period.

Group Type ACTIVE_COMPARATOR

tadalafil

Intervention Type DRUG

20 mg tadalafil as needed by mouth no more than once a day for a 4 week initiation period and a 4 weeks treatment period.

Interventions

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tadalafil

20 mg tadalafil as needed by mouth no more than once a day for a 4 week initiation period and a 4 weeks treatment period.

Intervention Type DRUG

sildenafil

Current dosage of sildenafil is continued for 4 weeks (no more than once a day) of treatment assessment then the wash-out period will begin.

Intervention Type DRUG

Other Intervention Names

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LY450190 Cialis IC351

Eligibility Criteria

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Inclusion Criteria

* Must be of legal age according to your country.
* Must have had a history of erectile dysfunction for at least 3 months.
* Must currently and have been using sildenafil for the last six weeks.
* Agree to not use any other ED treatment during the study.
* Anticipate the same female sexual partner for the study.

Exclusion Criteria

* History of other primary sexual disorder
* Treatment with nitrates
* Have a penile implant or clinically significant penile deformity
* History of certain heart problems
* Do not meet certain lab value reference ranges
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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ICOS Corporation

INDUSTRY

Sponsor Role collaborator

Eli Lilly and Company

INDUSTRY

Sponsor Role lead

Principal Investigators

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Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern Time (UTC/GMT - 5 hours, EST)

Role: STUDY_DIRECTOR

Eli Lilly and Company

Locations

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

São Paulo, , Brazil

Site Status

Countries

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Brazil

Other Identifiers

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H6D-VI-LVFH

Identifier Type: -

Identifier Source: secondary_id

7925

Identifier Type: -

Identifier Source: org_study_id