Arterial Stiffness and Calcifications in Incident Renal Transplant Recipients
NCT ID: NCT00547040
Last Updated: 2018-10-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
304 participants
OBSERVATIONAL
2006-10-31
2013-10-31
Brief Summary
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* Natural history of calcification posttransplantation
* Natural history of BMC following renal transplantation
* Reverse correlation between calcification score and aortic calcifications following renal transplantation
* Correlation of IMT, BMC, PWV and biochemical variables
* Correlation of IMT, BMC, PWV, biochemical variables and outcome
* Predictors of CV disease after transplantation
* Predictors of IMT progression, BMC loss and PWV progression after renal transplantation
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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A
incident renal transplant patients
no intervention
no intervention
Interventions
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no intervention
no intervention
Eligibility Criteria
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Inclusion Criteria
18 Years
90 Years
ALL
No
Sponsors
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Universitaire Ziekenhuizen KU Leuven
OTHER
Responsible Party
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Kathleen Claes
md
Principal Investigators
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kathleen Claes, MD
Role: PRINCIPAL_INVESTIGATOR
UZ Leuven
Locations
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UZ Gasthuisberg
Leuven, , Belgium
Countries
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References
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Jorgensen HS, Claes K, Smout D, Naesens M, Kuypers D, D'Haese P, Cavalier E, Evenepoel P. Associations of Changes in Bone Turnover Markers with Change in Bone Mineral Density in Kidney Transplant Patients. Clin J Am Soc Nephrol. 2024 Apr 1;19(4):483-493. doi: 10.2215/CJN.0000000000000368. Epub 2023 Nov 29.
Evenepoel P, Claes K, Viaene L, Bammens B, Meijers B, Naesens M, Sprangers B, Kuypers D. Decreased Circulating Sclerostin Levels in Renal Transplant Recipients With Persistent Hyperparathyroidism. Transplantation. 2016 Oct;100(10):2188-93. doi: 10.1097/TP.0000000000001311.
Claes KJ, Heye S, Bammens B, Kuypers DR, Meijers B, Naesens M, Vanrenterghem Y, Evenepoel P. Aortic calcifications and arterial stiffness as predictors of cardiovascular events in incident renal transplant recipients. Transpl Int. 2013 Oct;26(10):973-81. doi: 10.1111/tri.12151. Epub 2013 Jul 19.
Other Identifiers
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ML3775
Identifier Type: -
Identifier Source: org_study_id
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