BEATRIS Study: A Study of Adherence to Bonviva (Ibandronate) Once Monthly in Women With Post-Menopausal Osteoporosis

NCT ID: NCT00545909

Last Updated: 2016-11-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

585 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-03-31

Study Completion Date

2008-08-31

Brief Summary

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This 2 arm study will assess the impact of Bone Marker Feedback (BMF), using blood sampling and communication of the results at 2 months, on adherence to monthly Bonviva (150mg po) in women with post-menopausal osteoporosis. Patients will be randomized into either 1) a group which receives bone marker feedback or 2)a group which does not receive feedback on the results. The study will also assess patient satisfaction with treatment with once monthly Bonviva. The anticipated time on study treatment is 3-12 months, and the target sample size is 500+ individuals.

Detailed Description

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Conditions

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Postmenopausal Osteoporosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

Group Type EXPERIMENTAL

ibandronate [Bonviva/Boniva]

Intervention Type DRUG

150mg po monthly for 6 months (+ feedback)

2

Group Type ACTIVE_COMPARATOR

ibandronate [Bonviva/Boniva]

Intervention Type DRUG

150mg po monthly for 6 months (- feedback)

Interventions

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ibandronate [Bonviva/Boniva]

150mg po monthly for 6 months (+ feedback)

Intervention Type DRUG

ibandronate [Bonviva/Boniva]

150mg po monthly for 6 months (- feedback)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* ambulatory post-menopausal women with osteoporosis;
* 55-85 years of age;
* eligible for bisphosphonate treatment;
* naive to bisphosphonate therapy, or lapsed users (last bisphosphonate intake \> 6 months ago).

Exclusion Criteria

* inability to stand or sit in an upright position for at least 60 minutes;
* inability to swallow a tablet whole;
* hypersensitivity to bisphosphonates;
* administration of any drug, or presence of active disease, known to influence bone metabolism;
* uncorrected hypocalcemia or other bone disturbances of bone and mineral metabolism;
* history of major upper gastrointestinal disease.
Minimum Eligible Age

55 Years

Maximum Eligible Age

85 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Hoffmann-La Roche

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Trials

Role: STUDY_DIRECTOR

Hoffmann-La Roche

Locations

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Bregenz, , Austria

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Graz, , Austria

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Innsbruck, , Austria

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Linz, , Austria

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Salzburg, , Austria

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Vienna, , Austria

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Vienna, , Austria

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Vienna, , Austria

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Vienna, , Austria

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Vienna, , Austria

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Vienna, , Austria

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Vöcklabruck, , Austria

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Aalst, , Belgium

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Antwerp, , Belgium

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Antwerp, , Belgium

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Aye, , Belgium

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Braine-l'Alleud, , Belgium

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Bruges, , Belgium

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Brussels, , Belgium

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Brussels, , Belgium

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Brussels, , Belgium

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Brussels, , Belgium

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Brussels, , Belgium

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Charleroi, , Belgium

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Dinant, , Belgium

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Ekeren, , Belgium

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Genk, , Belgium

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Ghent, , Belgium

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Godinne, , Belgium

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Hasselt, , Belgium

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Jambes, , Belgium

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Knokke, , Belgium

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Kortrijk, , Belgium

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La Louvière, , Belgium

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Liège, , Belgium

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Liège, , Belgium

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Mechelen, , Belgium

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Merksem, , Belgium

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Mons, , Belgium

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Ostend, , Belgium

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Roeselare, , Belgium

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Sijsele, , Belgium

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Tournai, , Belgium

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Turnhout, , Belgium

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Waremme, , Belgium

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Wilrijk, , Belgium

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Athens, , Greece

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Athens, , Greece

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Kifissia, , Greece

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Larissa, , Greece

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Thessaloniki, , Greece

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Thessaloniki, , Greece

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Thessaloniki, , Greece

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Gorey, , Ireland

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Tipperary, , Ireland

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Luxembourg, , Luxembourg

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Luxembourg, , Luxembourg

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Countries

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Austria Belgium Greece Ireland Luxembourg

Other Identifiers

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ML19913

Identifier Type: -

Identifier Source: org_study_id