Comparison of Enteral Products for Tube Fed Patients With Type 2 Diabetes

NCT ID: NCT00544206

Last Updated: 2008-09-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

11 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-10-31

Study Completion Date

2008-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To compare the glucose response in tube fed subjects with type 2 diabetes of a standard enteral product to that of a diabetes-specific enteral product

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Type 2 Diabetes Mellitus

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

#1

Diabetes specific enteral feeding product

Group Type EXPERIMENTAL

Diabetes specific feeding product

Intervention Type OTHER

16 hrs daily for 5 days

#2

Standard enteral feeding product

Group Type ACTIVE_COMPARATOR

standard enteral feeding product

Intervention Type OTHER

16 hrs daily x 5 days

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

standard enteral feeding product

16 hrs daily x 5 days

Intervention Type OTHER

Diabetes specific feeding product

16 hrs daily for 5 days

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* signed and dated informed consent
* diagnosis of type 2 diabetes
* HbA1c between 7.0 and 9.0%
* 18 - 75 years of age
* currently receiving a standard enteral product
* anticipated duration on tube feeding at least one month
* 100% of patient's nutrient and energy needs are anticipated to be met by enteral nutrition support
* anticipated life expectancy is more than or equal to 6 months
* free of infections
* no change in medications within 2 weeks prior to screening that could profoundly affect blood glucose

Exclusion Criteria

* composition of either product is inappropriate for the patient due to allergies or intolerance to any ingredient found in the study products
* composition of either product is inappropriate for the patient due to protein, fluid or electrolyte restrictions for concomitant conditions
* significant cardiovascular event less than or equal to 2 weeks prior to study entry
* major surgery less than or equal to 2 weeks prior to study entry
* pre-planned surgery during the study period
* active malignancy, including melanoma and excluding cutaneous malignancies
* severe dementia
* known allergies to medical grade adhesives and/or skin disinfectants
* taking octreotide
* chronic, contagious, infectious disease, such as active tuberculosis, Hepatitis B or C, or HIV
* participation in a concomitant trial
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Abbott Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Abbott Nutrition

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Gordon Sacks, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Wisconsin, Madison

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Segal Institute for Clinical Research

Miami, Florida, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

References

Explore related publications, articles, or registry entries linked to this study.

Alish CJ, Garvey WT, Maki KC, Sacks GS, Hustead DS, Hegazi RA, Mustad VA. A diabetes-specific enteral formula improves glycemic variability in patients with type 2 diabetes. Diabetes Technol Ther. 2010 Jun;12(6):419-25. doi: 10.1089/dia.2009.0185.

Reference Type DERIVED
PMID: 20470226 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

BK07

Identifier Type: -

Identifier Source: org_study_id