Bacterial Vaginosis; A Randomized Trial to Reduce Recurrence

NCT ID: NCT00542074

Last Updated: 2007-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

223 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-06-30

Study Completion Date

2005-08-31

Brief Summary

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Randomized controlled trial (RCT) to evaluate the effectiveness of applying Purell® (62% ethyl alcohol in emollient gel) to the penis of male partners of women diagnosed with BV for preventing BV recurrence after treatment.

Detailed Description

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Conditions

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Bacterial Vaginosis

Keywords

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Bacterial vaginosis recurrence male factor

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Caregivers Investigators Outcome Assessors

Study Groups

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1

Group Type EXPERIMENTAL

hygienic information plus 62% ethyl alcohol in emollient gel

Intervention Type OTHER

The male partner in each couple was asked to apply Purell® to his penis at least daily, and immediately prior to and following intercourse. Couples received a brochure with information on control of STI and good hygienic practices. Brochures for intervention and control arms were similar except the intervention arm brochure provided information on how to use the study product (Purell®).

2

Group Type ACTIVE_COMPARATOR

hygienic information

Intervention Type OTHER

Couples received a brochure with information on control of STI and good hygienic practices.

Interventions

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hygienic information plus 62% ethyl alcohol in emollient gel

The male partner in each couple was asked to apply Purell® to his penis at least daily, and immediately prior to and following intercourse. Couples received a brochure with information on control of STI and good hygienic practices. Brochures for intervention and control arms were similar except the intervention arm brochure provided information on how to use the study product (Purell®).

Intervention Type OTHER

hygienic information

Couples received a brochure with information on control of STI and good hygienic practices.

Intervention Type OTHER

Other Intervention Names

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Purell® (GOJO Healthcare Inc., Akron, OH)

Eligibility Criteria

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Inclusion Criteria

* Vaginal symptoms
* Nugent score \> 6 for vaginal fluid gram stain
* Woman and her male partner both interested in study participation
* Woman able to return for follow-up visits
* Woman able to provide detailed contact information for tracing

Exclusion Criteria

* Either male or female partner not recruited within 24 hours of the other
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fogarty International Center of the National Institute of Health

NIH

Sponsor Role collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

Sponsor Role collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

Sponsor Role collaborator

University of Washington

OTHER

Sponsor Role lead

Principal Investigators

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King K. Holmes, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Washington

Locations

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Nairobi City Council STI referral clinic (Special Treatment Clinic)

Nairobi, , Kenya

Site Status

Countries

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Kenya

Other Identifiers

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R03TW005820

Identifier Type: NIH

Identifier Source: secondary_id

View Link

HD 40540-04

Identifier Type: -

Identifier Source: secondary_id

P30AI027757

Identifier Type: NIH

Identifier Source: secondary_id

View Link

01-9276-001

Identifier Type: -

Identifier Source: org_study_id