GORE VIABAHN Endoprosthesis With Heparin Bioactive Surface in the Treatment of SFA Obstructive Disease (VIPER)

NCT ID: NCT00541307

Last Updated: 2012-12-27

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

119 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-10-31

Study Completion Date

2011-06-30

Brief Summary

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The objective of the study is collect data on the GORE VIABAHN Endoprosthesis with Heparin Bioactive Surface in the treatment of chronic Superficial Femoral Artery disease. Device patency at 12 months is the primary endpoint.

Detailed Description

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Conditions

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Peripheral Vascular Diseases

Keywords

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Peripheral Arterial Disease Peripheral Vascular Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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GORE VIABHAN Endoprothesis

Treatment with the GORE VIABAHN Endoprosthesis with Heparin Bioactive Surface

Group Type EXPERIMENTAL

Treatment with the GORE VIABAHN Endoprosthesis with Heparin Bioactive Surface

Intervention Type DEVICE

Endovascular treatment of the study lesion with the GORE VIABAHN Endoprosthesis with Heparin Bioactive Surface

Interventions

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Treatment with the GORE VIABAHN Endoprosthesis with Heparin Bioactive Surface

Endovascular treatment of the study lesion with the GORE VIABAHN Endoprosthesis with Heparin Bioactive Surface

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* lifestyle limiting claudication, rest pain or minor tissue loss\>
* ABI (ankle-brachial index) \< 0.9 or TBI (toe-brachial index) \< 0.5 if ABI is \>0.9
* Stenosis (\>50%) or occlusion of native SFA (superficial femoral artery) \>5cm
* Orifice and 1 cm of SFA are patent
* Popliteal artery is patent at the intercondylar fossa of the femur to the trifurcation
* At least 1 patent run off vessel
* Guidewire and deliver system successfully traversed the lesion

Exclusion Criteria

* Untreated flow-limiting aortoiliac occlusive disease
* Any previous stenting or surgery in the target vessel
* Femoral or popliteal aneurysm of target vessel
* No patent tibial arteries
* Prior ipsilateral femoral artery bypass
* Major distal amputation (above the transmetatarsal) in either limb
* Patients with known sensitivity to Heparin
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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W.L.Gore & Associates

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Richard Saxon, MD

Role: PRINCIPAL_INVESTIGATOR

North County Radiology Medial Group Inc.

Locations

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Tri-City Medical Center

Oceanside, California, United States

Site Status

Mercy Hospital and Medical Center

Chicago, Illinois, United States

Site Status

Columbia Surgical Associates

Columbia, Missouri, United States

Site Status

Baylor University Medical Center

Dallas, Texas, United States

Site Status

St. Luke's Medical Center

Milwaukee, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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VPR 07-03

Identifier Type: -

Identifier Source: org_study_id