Blue-Blocking IOLs in Combined Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-10-31

Study Completion Date

2006-03-31

Brief Summary

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Although commonly used in cataract surgery, the use of the blue light-filter IOLs in vitrectomy combined with cataract surgery has not been reported yet. A prospective controlled clinical trial was designed to evaluate the effect of the blue light-filter IOL on the surgeon's ability to perform specific vitreoretinal procedures and on the patients' outcome.

Detailed Description

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Sixty patients were randomly assigned to receive a UV-filter IOL (transparent IOL group) or a blue light-filter IOL (yellow IOL group) combined with a vitreoretinal procedure.

Outcome measures were intraoperative conditions for the surgeon, complication rates, the functional outcome and vitreoretinal diagnoses.

Conditions

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Epiretinal Membranes Macular Holes Cataract

Keywords

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combined surgery, cataract surgery, vitrectomy, blue light-filter iols

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Interventions

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combined surgery

UV-filter IOL (transparent IOL group) or a blue light-filter IOL (yellow IOL group) combined with a vitreoretinal procedure

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Diagnosis vitreoretinal pathology (diabetic vitreous hemorrhage, macular hole, epiretinal membrane or persisting macula edema)
* Coexisting significant cataract
* The need for combined surgery ( pars plana vitrectomy, phacoemulsification and IOL implantation)
* Age over 50 years.

Exclusion Criteria

* Pseudophakia on the non-study eye
* The need for silicone oil tamponade
* Optic atrophy.

Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Principal Investigators

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Susanne Binder, Prof., MD

Role: PRINCIPAL_INVESTIGATOR

Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery

Christiane I Falkner-Radler, MD

Role: STUDY_DIRECTOR

Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery

References

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Hayashi K, Hayashi H. Visual function in patients with yellow tinted intraocular lenses compared with vision in patients with non-tinted intraocular lenses. Br J Ophthalmol. 2006 Aug;90(8):1019-23. doi: 10.1136/bjo.2006.090712. Epub 2006 Apr 5.

Reference Type BACKGROUND

PMID: 16597662 (View on PubMed)

Olson RJ, Werner L, Mamalis N, Cionni R. New intraocular lens technology. Am J Ophthalmol. 2005 Oct;140(4):709-16. doi: 10.1016/j.ajo.2005.03.061. Epub 2005 Jul 18.

Reference Type BACKGROUND

PMID: 16023990 (View on PubMed)

Falkner-Radler CI, Benesch T, Binder S. Blue light-filter intraocular lenses in vitrectomy combined with cataract surgery: results of a randomized controlled clinical trial. Am J Ophthalmol. 2008 Mar;145(3):499-503. doi: 10.1016/j.ajo.2007.10.021. Epub 2008 Jan 11.

Reference Type DERIVED

PMID: 18191090 (View on PubMed)

Other Identifiers

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FR-CI-03-2007

Identifier Type: -

Identifier Source: org_study_id