Evaluation of Safety and Efficacy of Symbicort® pMDI, With or Without Spacer, in Children (6-11 Years) With Asthma

NCT ID: NCT00536913

Last Updated: 2012-04-06

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

107 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-09-30

Study Completion Date

2008-02-29

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of the study is to compare Symbicort pMDI with and without spacer in terms of steroid potency, improvement of lung function and asthma symptoms in children with asthma (6-11 years).

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Asthma

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

With Spacer

Budesonide/formoterol pMDI 40/2.25ug + spacer

Group Type EXPERIMENTAL

Budesonide/formoterol pMDI 40/2.25ug + spacer

Intervention Type DRUG

Without Spacer

Budesonide/formoterol pMDI 40/2.25 ug

Group Type EXPERIMENTAL

Budesonide/formoterol pMDI 40/2.25 ug

Intervention Type DRUG

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Budesonide/formoterol pMDI 40/2.25ug + spacer

Intervention Type DRUG

Budesonide/formoterol pMDI 40/2.25 ug

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* children 6-11 years, diagnosed asthma treated
* 6 months, PEF
* 50% of predicted normal value pre-bronchodilator

Exclusion Criteria

* current systemic glucocorticosteroids usage
* current respiratory infection
* any significant disease or disorder as judged by investigator
Minimum Eligible Age

6 Years

Maximum Eligible Age

11 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

AstraZeneca

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Tomas Anderson, MD PhD

Role: STUDY_DIRECTOR

AstraZeneca

Piotr Kuna, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Uniwersytecki Spital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Research Site

Budapest, , Hungary

Site Status

Research Site

Debrecen, , Hungary

Site Status

Research Site

Kaposvár, , Hungary

Site Status

Research Site

Bialystok, , Poland

Site Status

Research Site

Bydgoszcz, , Poland

Site Status

Research Site

Bytom, , Poland

Site Status

Research Site

Karpacz, , Poland

Site Status

Research Site

Krakow, , Poland

Site Status

Research Site

Lodz, , Poland

Site Status

Research Site

Warsaw, , Poland

Site Status

Research Site

Moscow, , Russia

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Hungary Poland Russia

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

D5897C00004

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Gemini Symbicort pMDI
NCT00646516 COMPLETED PHASE3