Evaluating the Relationship Between Tobacco Use, Anxiety Sensitivity, and Panic in Adolescents

NCT ID: NCT00535964

Last Updated: 2022-11-17

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 180 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2007-06-30
• Study Completion Date: 2009-04-30

Brief Summary

This study will determine whether there is a relationship between tobacco use and a heightened response to panic-producing events among adolescents. This study is fundamental research. It was not a Clinical Trial.

Detailed Description

Growing up is hard enough, and adolescence can be a particularly stressful time in people's lives as they adjust to the transition from childhood to adulthood. Peer pressure can add to this anxiety, making it more likely for teens to take part in risky behaviors such as smoking cigarettes. Every day, more than 4,000 teens smoke their first cigarette and nearly half of those teens will become regular, daily smokers. Cigarette smoking is associated with a multitude of health risks, including an increased likelihood of experiencing panic attacks, anxiety disorders, and depression. This study will evaluate a group of teens, ranging from those who have never smoked to those who smoke daily, to determine whether there is a relation between adolescent smoking history and their vulnerability to panic-producing situations.

Participants in this study will undergo a brief medical screening, followed by a short interview that will include several questionnaires regarding emotions, experiences, and personal habits. Participants will then attend a series of laboratory assessments for 1 hour. The first assessment will include a 3-minute voluntary hyperventilation procedure in which participants will be directed when to breathe in and when to breathe out, at a faster rate than normal. Participants will then take part in two computerized tasks: one will be a computerized task that involves blowing up a balloon and deciding when to quit before the balloon pops; the other task will involve choosing hypothetical amounts of money now or after a period of delay. During the laboratory assessments, all participants will have electrodes attached to their bodies and sensors around their chests to measure heart rate, palm sweating, and muscle tension. Results from this study will be used to evaluate the association between smoking and increased panic levels under stressful conditions among adolescents.

Conditions

Panic Disorder

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

1

Psychologically healthy adolescents, evenly divided across the various stages of smoking uptake

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Adolescents, ranging from those who have never smoked to those who smoke daily

Exclusion Criteria

• Current or past diagnosis of a panic disorder
• Acute or chronic cardiopulmonary or respiratory illness (e.g., asthma or bronchitis)
• Pregnant

• Minimum Eligible Age: 12 Years
• Maximum Eligible Age: 17 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

National Institute of Mental Health (NIMH)

NIH

Sponsor Role: collaborator

University of Arkansas, Fayetteville

OTHER

Sponsor Role: lead

Responsible Party

Ellen Leen-Feldner

Professor of Psychology

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Ellen W. Leen-Feldner, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Arkansas

Locations

University of Arkansas

Fayetteville, Arkansas, United States

Countries

United States

Other Identifiers

R03MH077692

Identifier Type: NIH

Identifier Source: secondary_id

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DAHBR 96-BHB

Identifier Type: -

Identifier Source: secondary_id

R03MH077692

Identifier Type: NIH

Identifier Source: org_study_id

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