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Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population

NCT ID: NCT00533754

Last Updated: 2007-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2006-07-31

Study Completion Date

2007-11-30

Brief Summary

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The aim of the study is to show a higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals.

Additionaly a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD.

Detailed Description

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Conditions

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Age-Related Macular Degeneration

Keywords

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age-related macular degeneration, genetics

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Outcome Assessors

Interventions

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drawing blood

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* man and women over 18 years old
* Filled out informed consentBereitschaft zur Teilnahme
* Diagnosis of non-exudative/ exudative age related macular dgeneneration

Exclusion Criteria

* inherited retinal diseases
* other aquired retinal/ macular
* missing informed consent
Minimum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rudolf Foundation Clinic

OTHER

Sponsor Role lead

Principal Investigators

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Susanne Binder, M.D.

Role: STUDY_CHAIR

Rudoulf Foundation Clinic

Locations

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Rudoulf foundation Clinic

Vienna, Vienna, Austria

Site Status

Countries

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Austria

Other Identifiers

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EK 06-076-VK

Identifier Type: -

Identifier Source: secondary_id

EK 06-076-VK

Identifier Type: -

Identifier Source: org_study_id