Use of Oral Contraceptives (OCs) Containing Dienogest and Risk of Venous Thromboembolism

NCT ID: NCT00523614

Last Updated: 2010-03-23

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

3400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-07-31

Study Completion Date

2008-06-30

Brief Summary

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The objective of this study is to compare the risk of venous thromboembolism (VTE) of oral contraceptives with non-use, focusing specifically on Valette® compared to other users of low estrogen dose combined oral contraceptives.

Detailed Description

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This is a population-based case-control study in Germany.

Cases are women who are between 15 and 49 years old with a diagnosis of venous thromboembolism (VTE). The VTE is diagnosed in Germany between January 2002 und December 2007.

Controls are women who are between 15 and 49 years old without a VTE diagnosis. About 4 controls matched by year of birth and region will be allocated to each case.

Both cases and controls will receive a similar self-administered questionnaire except of some case-specific questions which are not applicable for the controls.

Study participants will be asked for their informed consent. Data confidentiality will be ensured by the Berlin Center for Epidemiology and Health Research.

Conditions

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Venous Thromboembolism

Study Design

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Observational Model Type

CASE_CONTROL

Study Groups

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1: Cases

No interventions assigned to this group

2: Controls

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* cases: women with a venous thromboembolism who are between 15 and 49 years old
* control: women without a venous thromboembolism diagnosis who are between 15 and 49 years old

Exclusion Criteria

* women outside the defined age range
* women with severe language problems
* women who are not willing to participate
Minimum Eligible Age

15 Years

Maximum Eligible Age

49 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role collaborator

Center for Epidemiology and Health Research, Germany

OTHER

Sponsor Role lead

Responsible Party

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Center for Epidemiology and Health Research, Germany

Principal Investigators

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Juergen C Dinger, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Center for Epidemiology and Health Research

Locations

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Center for Epidemilogy and Health Research

Berlin, , Germany

Site Status

Countries

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Germany

Other Identifiers

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ZEG2007_02

Identifier Type: -

Identifier Source: org_study_id

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