Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
OBSERVATIONAL
Brief Summary
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Detailed Description
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Conditions
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Study Design
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DEFINED_POPULATION
PROSPECTIVE
Study Groups
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Normal
Embryos derived from morphologically normal MII oocytes
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Irregular Shapes
Embryos derived from irregularly shaped oocytes.
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Large PVS
Embryos derived from oocytes with large perivitelline space.
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Dark Zona
Embryos derived from oocytes with dark zona pellucida
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Dark cytoplasm
Embryos derived from oocytes with dark cytoplasm
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Vacuolar cytoplasm
Embryos derived from oocytes with vacuolated cytoplasm
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Central granulation
Embryos derived from oocytes with centrally granulated cytoplasm
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Double extra
Embryos derived from oocytes with double extracytoplasmic abnormalities
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Double combined
Embryos derived from oocytes with any combination of one extracytoplasmic and one cytoplasmic anomaly
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Double cytoplasmic
Embryos derived from oocytes with any two cytoplasmic anomalies
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Triple extra
Embryos derived from oocytes with triple extracytoplasmic anomaly
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Triple combined
Embryos derived from oocytes with triple combined anomalies
Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Interventions
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Cryopreservation, thawing and blastocyst culture
Good quality human embryos were frozen - thawed and cultured to the blastocyst stage.
Eligibility Criteria
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Inclusion Criteria
* Embryos were obtained from couples who refused to freeze their supernumerary embryos after fresh embryo transfer in an assisted reproduction treatment cycle.
Exclusion Criteria
* Embryos obtained from abnormally fertilized zygotes.
18 Years
45 Years
FEMALE
No
Sponsors
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V.K.V. American Hospital, Istanbul
OTHER
Principal Investigators
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Basak Balaban, B.Sc.
Role: STUDY_DIRECTOR
Assisted Reproduction Unit of the VKV American Hospital of Istanbul
Locations
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VKV American Hospital
Istanbul, , Turkey (Türkiye)
Countries
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References
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Balaban B, Ata B, Isiklar A, Yakin K, Urman B. Severe cytoplasmic abnormalities of the oocyte decrease cryosurvival and subsequent embryonic development of cryopreserved embryos. Hum Reprod. 2008 Aug;23(8):1778-85. doi: 10.1093/humrep/den127. Epub 2008 May 12.
Other Identifiers
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AH-05/04
Identifier Type: -
Identifier Source: org_study_id