MedDataX Logo

The Effect of Calcium on Fecal Fat and Energy Excretion

NCT ID: NCT00519909

Last Updated: 2007-08-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-08-31

Study Completion Date

2008-02-29

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The overall purpose of this study is to examine the effect of calcium on fecal fat and energy excretion.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Several reports have found inverse associations between calcium intake and body weight. Few intervention studies have shown that a high calcium diet resulted in a greater body weight loss than a low calcium diet. The mechanism is not clear, but one possible explanation is reduced absorption of fat in the gut, due to formation of insoluble calcium fatty acid soaps or binding of bile acids which impairs the formation of micelles.

The aim of this study is to examined if a high calcium intake from dairy products, in diets high or normal in fat content, have an effect on fecal energy and fat excretion, concentrations of substrates involved in energy metabolism and blood pressure.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Obesity

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

1

Diet with high content of calcium and high content of fat

Group Type OTHER

Dairy calcium

Intervention Type OTHER

Diets with different content of calcium and fat

2

Diet with low content of calcium and high content of fat

Group Type OTHER

Dairy calcium

Intervention Type OTHER

Diets with different content of calcium and fat

3

Diet with high content of calcium and normal content of fat

Group Type OTHER

Dairy calcium

Intervention Type OTHER

Diets with different content of calcium and fat

4

Diet with low content of calcium and normal content of fat

Group Type OTHER

Dairy calcium

Intervention Type OTHER

Diets with different content of calcium and fat

5

Diet with high content of calcium fra supplement and high content of fat

Group Type OTHER

Dairy calcium

Intervention Type OTHER

Diets with different content of calcium and fat

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Dairy calcium

Diets with different content of calcium and fat

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* healthy meals
* BMI 24-31 kg/m2
* age between 18-50 years

Exclusion Criteria

* donation of blood 6 months before and under the study
* milk allergy, diabetes, hypertension, hyperlipidemia, cronic infectious disease
* use of dietary supplements 3 months before and under the study
* smoking
* elite athletes
* use of medication
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Arla Foods

INDUSTRY

Sponsor Role collaborator

The Danish Dairy Research Foundation, Denmark

OTHER

Sponsor Role collaborator

FOOD Graduate School, the Royal Veterinary & Agricultural University, Denmark

OTHER

Sponsor Role collaborator

Danish Research Agency

OTHER

Sponsor Role collaborator

University of Copenhagen

OTHER

Sponsor Role lead

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Janne K Lorenzen, PhD student

Role: PRINCIPAL_INVESTIGATOR

Dept. of Human Nutrition, Faculty of Life Sciences, Univerity of Copenhagen

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Dept. of Human Nutrition, Faculty of Life Sciences, University of Copenhagen

Frederiksberg, , Denmark

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Denmark

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Arne Astrup, Prof. MD

Role: CONTACT

[email protected]
+45 3533 2476

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Arne Astrup, prof. MD

Role: primary

[email protected]
+45 3533 2476

Janne K Lorenzen, PhD student

Role: backup

[email protected]
+45 3533 3632

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

H-KF-01-144/02

Identifier Type: -

Identifier Source: org_study_id