Fatigue Intervention Trial for Breast Cancer Survivors

NCT ID: NCT00513136

Last Updated: 2019-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-05-31

Study Completion Date

2009-02-28

Brief Summary

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Thirty to forty percent of breast cancer survivors suffer from persistent fatigue lingering months to years after adjuvant therapy is completed. Although researchers have developed some effective interventions (exercise or group-based holistic program) to treat fatigue, none have addressed the role of the family in the patient's long-term recovery.

The investigators hypothesize that a family-focused intervention in combination with a mind-body group intervention will be more effective in reducing fatigue, improving quality of life, and enhancing family relationships for breast cancer survivors than a group intervention with an individual focus.

Detailed Description

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We propose to address the persistent fatigue experienced by brest cancer survivors by using a 10 week group-based mind body medicine intervention that includes the family in the process. We believe that this family-centered approach can facilitate better communication, create shared illness experience and relieve conflict. Reducing this pervasive source of stress will not only reduce the survivor's fatigue, but also foster an opposite family dynamic with positive effects in many other aspects of post-treatment recovery. We will compare the effectiveness of a 10 week group intervention to a 10 week group intervention that includes a family focus.

Breast cancer survivors with moderate to severe fatigue will be randomly assigned to one of the two groups and we will measure change in fatigue, quality of life, mood and social support from baseline to end-of-program and then two and six months after program completion.

Conditions

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Fatigue

Keywords

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Fatigue Breast Cancer Behavioral Research Quality of Life

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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I

10 week group-based mind body medicine intervention

Group Type ACTIVE_COMPARATOR

Group based mind body medicine intervention

Intervention Type BEHAVIORAL

Small groups of women (5-15) will participate in 10 weekly sessions that will include learning relaxation and yoga techniques, principles of exercise and nutrition, cognitive behavioral therapy and exploration of common issues and concerns

II

Group-based mind body medicine intervention with a family focus

Group Type EXPERIMENTAL

Group-based mind body medicine intervention + family focus

Intervention Type BEHAVIORAL

In addition to the 10 weekly group-based sessions, women and their key family members will meet twice with a cognitive therapist and family members will participate in selected aspects of the 10 week program.

Interventions

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Group based mind body medicine intervention

Small groups of women (5-15) will participate in 10 weekly sessions that will include learning relaxation and yoga techniques, principles of exercise and nutrition, cognitive behavioral therapy and exploration of common issues and concerns

Intervention Type BEHAVIORAL

Group-based mind body medicine intervention + family focus

In addition to the 10 weekly group-based sessions, women and their key family members will meet twice with a cognitive therapist and family members will participate in selected aspects of the 10 week program.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Stage I-III Breast Cancer
* At least 3 months since last breast cancer treatment (excluding hormonal therapy or Herceptin).
* 4 week history of persistent moderate to severe fatigue
* Competent to sign informed consent
* Willing to be randomized

Exclusion Criteria

* Metastatic breast cancer
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Mercy Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Michael Mullen

Administration

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kathy J Helzlsouer, MD, MHS

Role: PRINCIPAL_INVESTIGATOR

Mercy Medical Center

Julianne Oktay, PhD, MSW

Role: PRINCIPAL_INVESTIGATOR

University of Maryland School of Social Work

Locations

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Mercy Medical Center

Baltimore, Maryland, United States

Site Status

Countries

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United States

Other Identifiers

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MMC2007-46

Identifier Type: -

Identifier Source: org_study_id