Effect of Tadalafil in Chronic Obstructive Lung Disease Patients Suffering From Secondary Pulmonary Hypertension

NCT ID: NCT00506701

Last Updated: 2015-03-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2008-02-29

Study Completion Date

2010-02-28

Brief Summary

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Tadalafil may lower the pulmonary artery pressure in patients with Chronic Obstructive Lung Disease and secondary pulmonary hypertension and thereby improve patients quality of life.

Detailed Description

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Twenty outpatients with Chronic Obstructive Lung Disease (COPD) and secondary pulmonary hypertension are treated in a cross-over design with Tadalafil or placebo for 4 weeks. Primary effect parameter is 6 min. walking test.

Conditions

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Chronic Obstructive Lung Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Tadalafil treatment 40 mg

Group Type EXPERIMENTAL

Tadalafil

Intervention Type DRUG

40 mg tablet

Interventions

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Tadalafil

40 mg tablet

Intervention Type DRUG

Other Intervention Names

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PDE5 inhibitor

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of Chronic obstructive lung disease

Exclusion Criteria

* Patients with asthma
Minimum Eligible Age

45 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Herlev Hospital

OTHER

Sponsor Role lead

Responsible Party

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Herlev Hospital

Principal Investigators

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Lars C Laursen, MD

Role: PRINCIPAL_INVESTIGATOR

University of Copenhagen

Locations

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Herlev University Hospital

Herlev, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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25

Identifier Type: -

Identifier Source: org_study_id

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