Dose-ranging Trial of OPC-249 Powder Inhalation in Patients With Pain Due to Osteoporosis

NCT ID: NCT00504426

Last Updated: 2014-01-30

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

101 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-07-31

Study Completion Date

2009-05-31

Brief Summary

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The purpose of this study is to examine the efficacy and safety of OPC-249 by once daily inhalation at 0 (placebo), 30, 60 or 120 IU for 4 weeks in patients with pain due to osteoporosis.

Detailed Description

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Conditions

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Pain Due to Osteoporosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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1

Group Type PLACEBO_COMPARATOR

OPC-249

Intervention Type DRUG

1 pugh/day for 4 weeks (30 IU, 60IU, or 90IU)

2

Group Type ACTIVE_COMPARATOR

OPC-249

Intervention Type DRUG

1 pugh/day for 4 weeks (30 IU, 60IU, or 90IU)

3

Group Type ACTIVE_COMPARATOR

OPC-249

Intervention Type DRUG

1 pugh/day for 4 weeks (30 IU, 60IU, or 90IU)

4

Group Type ACTIVE_COMPARATOR

OPC-249

Intervention Type DRUG

1 pugh/day for 4 weeks (30 IU, 60IU, or 90IU)

Interventions

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OPC-249

1 pugh/day for 4 weeks (30 IU, 60IU, or 90IU)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients who fulfill all of the following items

* Patients with primary osteoporosis
* Patients who have existing 1-4 vertebral fractures
* Patients with back pain persisting for one week or more
* Postmenopausal women between 46 and less than 80 years of age
Minimum Eligible Age

46 Years

Maximum Eligible Age

79 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Otsuka Pharmaceutical Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Katsuhisa Saito

Role: STUDY_DIRECTOR

Division of New Product Evaluation and Development

Locations

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Chubu Region, , Japan

Site Status

Hokkaido Region, , Japan

Site Status

Kanto Region, , Japan

Site Status

Kinki Region, , Japan

Site Status

Kyushu Region, , Japan

Site Status

Countries

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Japan

Other Identifiers

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249-06-002OD

Identifier Type: -

Identifier Source: org_study_id

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