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Transcranial and Rapid Magnetic Stimulation for Gait Apraxia Due to Normal Pressure Hydrocephalus and Cerebral Ischemia

NCT ID: NCT00494689

Last Updated: 2007-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-01-31

Study Completion Date

2007-06-30

Brief Summary

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The investigator(neurologist) has published a study in International Congress Series, in the 15th International Conference of Biomagnetism Vancouver Proceedings 2006,and Science Direct website, of 15 patients with brain ischemia and dilated ventricles who improve when treated with transcranial monitoring or low ultrasound wave intensity (milliwatts) and with rapid magnetic stimulation which is also a diagnostic tool routinely used by many neurophysiologists. Before, these patients will progress and may need a brain shunt called Ventriculo-peritoneal shunt. He and collaborators now would like to do a double study as this appears to be a cheap and effective alternative treatment and help patients to walk again.

Detailed Description

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The transcranial monitoring intensity would be equivalent to the well known CLOTBUST study (\<300mw/sq cm)for one hour, using two probes.

All will be treated as an outpatient and there is no form of infusion or interventional treatment.

The rapid magnetic stimulation is at about 50a/us, 15Hz, 1000 pulses with 10 sec pause for ten days along the skull vault. Informed consent will be obtained. 30 patients will be recruited and sham treatment would be just applying probe without power for transcranial and for magnetic stimulation coil will be angled away. Data will be compiled by a separate blinded investigator and so with the statistics. VP shunt failure patients, which is common, will be included. Barthel's daily living index and standard cognitive tests will be used to assess results.

Conditions

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Walking Cognitive Function

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* cerebral ischemia with our without hydrocephalus and gait apraxia

Exclusion Criteria

* all other conditions which contribute to walking difficulty e.g. bad knees; or spondylosis; parkinson's or paralytic strokes
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Devathasan Neurology Practice Pte Ltd

OTHER

Sponsor Role lead

Principal Investigators

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Weng Kiong Aw Yong, Bsc (QUT)

Role: STUDY_CHAIR

Freelancer Computer Programmer and data control

Locations

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Devathasan Neurology Practice #11-16 MEMC

Singapore, , Singapore

Site Status RECRUITING

Devathasan Neurology Practice

Singapore, , Singapore

Site Status RECRUITING

Countries

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Singapore

Central Contacts

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Devathasan Gobinathan, FRCP,MD

Role: CONTACT

[email protected]
65-67330311

Weng Kiong Ow Yong, Bsc

Role: CONTACT

[email protected]
65-97970966

Facility Contacts

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Gobinathan Devathasan, FRCP

Role: primary

[email protected]
65-97304401

References

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Devathasan G, Dinesh D. Rapid magnetic stimulation with sonolysis for gait apraxia due to to normal pressure hyprocephalus and cerebral ischemia. International Congress Series xx (2007)xxx-xxx( in press)

Reference Type BACKGROUND

Other Identifiers

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02

Identifier Type: -

Identifier Source: org_study_id