Trial Outcomes & Findings for Study to Investigate the Potential of Probiotics in Yogurt (NCT NCT00492583)

NCT ID: NCT00492583

Last Updated: 2011-08-17

Results Overview

Outcome measure, "number of days children are out of school sick" was measured for the entire population

Recruitment status

COMPLETED

Study phase

PHASE3

Target enrollment

182 participants

Primary outcome timeframe

90 days

Results posted on

2011-08-17

Participant Flow

Participant milestones

Participant milestones
Measure
Placebo
Bifidobacterium Lactis (BB-12)
Overall Study
STARTED
95
87
Overall Study
COMPLETED
95
87
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Study to Investigate the Potential of Probiotics in Yogurt

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Placebo
n=95 Participants
Bifidobacterium Lactis (BB-12)
n=87 Participants
Total
n=182 Participants
Total of all reporting groups
Age, Categorical
<=18 years
95 Participants
n=5 Participants
87 Participants
n=7 Participants
182 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Sex/Gender, Customized
Female
36 participants
n=5 Participants
43 participants
n=7 Participants
79 participants
n=5 Participants
Sex/Gender, Customized
Male
50 participants
n=5 Participants
34 participants
n=7 Participants
84 participants
n=5 Participants
Sex/Gender, Customized
Missing
9 participants
n=5 Participants
10 participants
n=7 Participants
19 participants
n=5 Participants
Region of Enrollment
United States
95 participants
n=5 Participants
87 participants
n=7 Participants
182 participants
n=5 Participants

PRIMARY outcome

Timeframe: 90 days

Outcome measure, "number of days children are out of school sick" was measured for the entire population

Outcome measures

Outcome measures
Measure
Placebo
n=95 Participants
Bifidobacterium Lactis (BB-12)
n=87 Participants
Number of Days Children Are Out of School Sick
2.51 days per 100 person days
2.82 days per 100 person days

Adverse Events

Placebo

Serious events: 0 serious events
Other events: 3 other events
Deaths: 0 deaths

Bifidobacterium Lactis (BB-12)

Serious events: 0 serious events
Other events: 3 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Placebo
n=95 participants at risk
Bifidobacterium Lactis (BB-12)
n=87 participants at risk
Gastrointestinal disorders
Diarrhea
3.2%
3/95 • Number of events 3
2.3%
2/87 • Number of events 2
General disorders
Pyrexia
0.00%
0/95
1.1%
1/87 • Number of events 1
Skin and subcutaneous tissue disorders
Dermatitis (Diaper)
3.2%
3/95 • Number of events 3
0.00%
0/87
Gastrointestinal disorders
Vomiting & Cough
3.2%
3/95 • Number of events 3
0.00%
0/87
Eye disorders
Hordeolum
1.1%
1/95 • Number of events 1
0.00%
0/87

Additional Information

Daniel J Merenstein, MD

Georgetown University

Phone: 202-687-2745

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place