Classroom Study to Assess Efficacy and Safety of MTS in Pediatric Patients Aged 6-12 With ADHD

NCT ID: NCT00466791

Last Updated: 2015-06-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

93 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-08-31

Study Completion Date

2005-05-31

Brief Summary

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Evaluate the behavioral effects of MTS in children aged 6-12 with ADHD

Detailed Description

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Evaluate the behavioral effects measured by the SKAMP deportment scale of MTS compared to placebo in children aged 6-12 with ADHD

Conditions

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Attention Deficit Disorder With Hyperactivity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Methylphenidate Transdermal System

Transdermal patch, 27.5mg, 41.3mg, 55mg, and 82.5mg, daily for 11 weeks

Group Type ACTIVE_COMPARATOR

Methylphenidate Transdermal System

Intervention Type DRUG

Placebo

Placebo

Transdermal patch, 0mg, daily for 11 weeks

Group Type PLACEBO_COMPARATOR

Methylphenidate Transdermal System

Intervention Type DRUG

Placebo

Interventions

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Methylphenidate Transdermal System

Placebo

Intervention Type DRUG

Other Intervention Names

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ADHD Patch

Eligibility Criteria

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Inclusion Criteria

* Primary diagnosis ADHD
* Total score of greater than or equal to 26 on ADHD-RS-IV
* IQ of greater than or equal to 80
* Blood pressure measurements within 95th percentile for age, gender, height at screening and baseline

Exclusion Criteria

* Current controlled (requiring a restricted medication) or uncontrolled, comorbid psychiatric diagnosis (except ODD)
* Known nonresponder to psychostimulant treatment
* BMI for age greater than 90th percentile
* History of seizures during last 2 years
* Conduct Disorder
Minimum Eligible Age

6 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Noven Therapeutics

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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UCI Child Development Center

Irvine, California, United States

Site Status

Countries

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United States

References

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McGough JJ, Wigal SB, Abikoff H, Turnbow JM, Posner K, Moon E. A randomized, double-blind, placebo-controlled, laboratory classroom assessment of methylphenidate transdermal system in children with ADHD. J Atten Disord. 2006 Feb;9(3):476-85. doi: 10.1177/1087054705284089.

Reference Type RESULT
PMID: 16481664 (View on PubMed)

Related Links

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Other Identifiers

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SPD485-201

Identifier Type: -

Identifier Source: org_study_id

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