Bronchodilatation Effects of a Small Volume Spacer Used With a Metered-Dose Inhaler
NCT ID: NCT00465413
Last Updated: 2007-11-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
300 participants
INTERVENTIONAL
2004-09-30
Brief Summary
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Detailed Description
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The purpose of the present study is to determine whether use of a small volume spacer is associated with better bronchodilatation in an unselected population of patients with documented reversible airflow limitations. The intervention in the first part of the study is use of an MDI with or without a spacer to deliver a bronchodilator (2 puffs, 0.4 mg of fenoterol). Spirometry is performed before and after the inhalation.
The second part of the study is conducted identically to the first with the same conditions and variables but with the addition of rinsing the mouth with 100 mL of water after inhaling the bronchodilator but before the second spirometry measurement.
The outcome to be measured is the increase in forced expiratory volume in 1 second (FEV1) and forced expiratory flow rate (FEF25-75%).
Conditions
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Keywords
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Interventions
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Small volume spacer and/or Rinsing the mouth with water
Eligibility Criteria
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Inclusion Criteria
* subjects known to have reversible airway limitation with demonstrated response to bronchodilators on spirometry.
Exclusion Criteria
* negative bronchodilator test,
* poor performance of pulmonary function testing.
6 Years
ALL
No
Sponsors
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Mackay Memorial Hospital
OTHER
Principal Investigators
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Ching-Lung Liu, MD
Role: STUDY_CHAIR
Mackay Memorial Taitung Branch Hospital
Yen-Ta Lu, MD, PhD.
Role: PRINCIPAL_INVESTIGATOR
Mackay Memorial Tamshui Branch Hospital
Locations
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Mackay Memorial Tamshui Branch Hospital
Tamshui, Taipei, Taiwan
Mackay Memorial Taitung Branch Hospital
Taitung, Taitung, Taiwan
Countries
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References
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Liu CL, Lu YT. Bronchodilatation effects of a small volume spacer used with a metered-dose inhaler. J Asthma. 2009 Sep;46(7):637-41. doi: 10.1080/02770900802492111.
Related Links
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Home page of Mackay Memorial Hospital
Other Identifiers
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MMH-I-S-317
Identifier Type: -
Identifier Source: org_study_id