Exercise and Activities for Independent Living With Mild Cognitive Impairment (MCI)
NCT ID: NCT00446394
Last Updated: 2012-10-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
181 participants
INTERVENTIONAL
2007-06-30
2012-10-31
Brief Summary
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Detailed Description
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Taken together, these prior investigations support the efficacy of behaviorally based exercise interventions in improving cognitive, physical, and affective status in cognitively intact and demented older adults. Results from a feasibility study suggest that these positive outcomes can also be obtained in older adults with MCI.
The current study will investigate the efficacy of the modified exercise program called RALLI (Resources and Activities for Life Long Independence) to determine whether it is more effective than the control condition, a social walking program (SW), in delaying cognitive decline, improving self-rated health and health behaviors, improving affect and physical function, and enhancing quality of life. The long-term efficacy of RALLI to delay conversion of MCI to dementia, reduce physical disability, maintain independent living, and improve physiological health indicators will also be investigated.
One hundred seventy participants over the age of 70 who meet American Academy of Neurology criteria for MCI will be recruited from independent living retirement residences. Participants will be randomly assigned to one of the two conditions (RALLI and SW) and assessed at baseline, post treatment (3 months), and follow up visits every 6 months for a total of 3 years (months 6, 12, 18, 24, 30, and 36). The hypothesis is that RALLI participants will experience better post-treatment outcomes than SW participants, and that gains will be maintained over 36 months.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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1
Resources and Activities for Life Long Independence (RALLI)
Strengthening exercises, encouragement to walk daily, pedometer reading, health promotion information for 1.5 hours weekly for 9 weeks
2
Social Walking program (SW)
Group support for walking, pedometer reading, 1 hour weekly for 9 weeks
Interventions
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Resources and Activities for Life Long Independence (RALLI)
Strengthening exercises, encouragement to walk daily, pedometer reading, health promotion information for 1.5 hours weekly for 9 weeks
Social Walking program (SW)
Group support for walking, pedometer reading, 1 hour weekly for 9 weeks
Eligibility Criteria
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Inclusion Criteria
* \- Memory complaint
* \- Objective memory impairment for age and education
* \- Largely intact general cognitive function
* \- Essentially preserved activities of daily living
* \- Not already diagnosed with dementia
* Insufficient physical activity defined as less than 150 minutes per week of moderate intensity physical activity
* Not currently in an exercise program similar to the study program
Exclusion Criteria
* Expected to move from the study geographic area during the study period
* Have a known terminal illness
* Actively suicidal, hallucinating, or delusional
* Hospitalized for a psychiatric disorder in the 12 months before baseline
* Uncontrolled chronic conditions, e.g. uncontrolled hypertension, unstable angina, uncontrolled blood glucose
* Blind or deaf
70 Years
ALL
No
Sponsors
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University of Washington
OTHER
Responsible Party
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Linda Teri
Professor
Principal Investigators
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Linda Teri, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Washington School of Nursing
Locations
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Northwest Research Group on Aging, Department of Psychosocial and Community Health, University of Washington School of Nursing
Seattle, Washington, United States
Countries
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Other Identifiers
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IA0100
Identifier Type: OTHER
Identifier Source: secondary_id
06-3067-C
Identifier Type: OTHER
Identifier Source: secondary_id
30692-J
Identifier Type: -
Identifier Source: org_study_id