Dreaming and EEG Changes During Anaesthesia Maintained With Propofol or Desflurane
NCT ID: NCT00446212
Last Updated: 2013-05-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
300 participants
INTERVENTIONAL
2006-08-31
2008-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
DOUBLE
Study Groups
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1
Propofol based anaesthetic maintenance with propofol effect-site steered target-controlled infusion, in addition to fentanyl and non-opioid analgesics
Propofol
target controlled infusion of propofol
2
Desflurane based anaesthetic maintenance with manually controlled administration in 100% oxygen in addition to fentanyl and non-opioid analgesics
desflurane
Anaesthetic maintenance with desflurane
Interventions
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Propofol
target controlled infusion of propofol
desflurane
Anaesthetic maintenance with desflurane
Eligibility Criteria
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Inclusion Criteria
* Age between 18 and 50 years
* Presenting for elective surgery under general anaesthesia
Exclusion Criteria
* Major drug abuse problem
18 Years
50 Years
ALL
No
Sponsors
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Melbourne Health
OTHER
Responsible Party
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Principal Investigators
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Kate Leslie, MD
Role: PRINCIPAL_INVESTIGATOR
Melbourne Health
Locations
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Royal Melbourne Hospital
Parkville, Victoria, Australia
Royal Perth Hospital
Perth, Western Australia, Australia
King Edward Memorial Hospital for Women
Subiaco, Western Australia, Australia
Waikato Hospital
Hamilton, , New Zealand
Countries
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References
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Liang Z, Wang Y, Ren Y, Li D, Voss L, Sleigh J, Li X. Detection of burst suppression patterns in EEG using recurrence rate. ScientificWorldJournal. 2014;2014:295070. doi: 10.1155/2014/295070. Epub 2014 Apr 17.
Leslie K, Sleigh J, Paech MJ, Voss L, Lim CW, Sleigh C. Dreaming and electroencephalographic changes during anesthesia maintained with propofol or desflurane. Anesthesiology. 2009 Sep;111(3):547-55. doi: 10.1097/ALN.0b013e3181adf768.
Other Identifiers
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2006.125
Identifier Type: -
Identifier Source: org_study_id
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