Fluorine F 18 FEQA in Patients With Stage III or Stage IV Non-Small Cell Lung Cancer and in Healthy Participants

NCT ID: NCT00444223

Last Updated: 2020-08-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

3 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-05-04

Study Completion Date

2008-05-15

Brief Summary

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RATIONALE: Fluorine F 18 FEQA may be an effective radioactive drug to use with positron emission tomography (PET) scans.

PURPOSE: This clinical trial is studying the use of fluorine F 18 FEQA in patients with stage III or stage IV non-small cell lung cancer and in healthy participants.

Detailed Description

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OBJECTIVES:

* Determine the biodistribution of fluorine F 18 FEQA in patients with stage III or IV non-small cell lung cancer (NSCLC) and in healthy participants.
* Determine whether fluorine F 18 FEQA can be used as an imaging agent with positron emission tomography in patients with stage III or IV NSCLC.

OUTLINE: This is a pilot study.

Patients and healthy participants receive fluorine F 18 FEQA IV and then undergo whole-body dynamic scans comprising positron emission tomography.

Blood is collected during and after imaging to measure radioactivity.

PROJECTED ACCRUAL: A total of 30 patients will be accrued for this study.

Conditions

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Lung Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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fluorine F 18 FEQA + positron emission tomography

Group Type EXPERIMENTAL

fluorine F 18 FEQA + positron emission tomography

Intervention Type PROCEDURE

Interventions

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fluorine F 18 FEQA + positron emission tomography

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Must meet 1 of the following criteria:
* Diagnosis of non-small cell lung cancer by CT scan, bone scan, or biopsy

* Stage III or IV disease
* Clinically assessed with
* Healthy participant
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Jonsson Comprehensive Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Johannes Czernin, MD

Role: STUDY_CHAIR

Jonsson Comprehensive Cancer Center

Locations

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Jonsson Comprehensive Cancer Center at UCLA

Los Angeles, California, United States

Site Status

Countries

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United States

Other Identifiers

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UCLA-0304039-01

Identifier Type: -

Identifier Source: secondary_id

CDR0000529363

Identifier Type: -

Identifier Source: org_study_id

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