MedDataX Logo

Substance Abuse Pre-Treatment Screening Study

NCT ID: NCT00439049

Last Updated: 2023-12-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

7500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-10-31

Study Completion Date

2026-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The overarching goal of this project is to have a consolidated consent and evaluation procedure that will lead potential subjects to the most appropriate clinical trial or human laboratory study (and its consent process) for their presenting concerns or interests. A second purpose is to have a consolidated intake data base on which secondary analyses can be conducted.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Approximately 1500 candidates per year will respond to advertisements and will complete preliminary telephone screening without identifiers. Appropriate candidates will be given appointment times and on arrival will undergo the consent process for evaluation. A complete medical, social, psychiatric, and drug use history will be obtained. Subjects fulfilling general health inclusion requirements will then be offered an appropriate study for which the specific consent will be obtained. The evaluation period will be no more than one day with all results evaluated within the two following days. Acceptable candidates will then be invited to complete the study specific consent.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cocaine Abuse Cocaine Dependence Opiate Dependence Alcohol Dependence Substance Abuse

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Substance Abuse Treatment Eligibility

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

A

Cocaine Dependent Subjects

modafinil

Intervention Type DRUG

400 mg daily

d-amphetamine

Intervention Type DRUG

60mg daily

L-Dopa

Intervention Type DRUG

800/200mg daily

Naltrexone

Intervention Type DRUG

50mg daily

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

modafinil

400 mg daily

Intervention Type DRUG

d-amphetamine

60mg daily

Intervention Type DRUG

L-Dopa

800/200mg daily

Intervention Type DRUG

Naltrexone

50mg daily

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Provigil Dexedrine Sinemet Revia

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Willing and able to participate in 3- to 6-month treatment program.
* At least 18 years of age.
* Seeking treatment for substances of abuse including (cocaine, opiates, and alcohol).
* Generally physically healthy.

Exclusion Criteria

* Pregnant or breastfeeding.
* Mandated by the courts/parole officers to attend treatment.
* Not seeking treatment for substances of abuse.
* Plans to move from the Houston area within the 3- to 6-month treatment period.
* Seeking treatment for a substance for which the Treatment Research Clinic (TRC) has no current trial.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

The University of Texas Health Science Center, Houston

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Joy Schmitz

Professor - Psy, Behavioral Science

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Joy M. Schmitz, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas Health Science Center, Houston

Frederick G Moeller, MD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas Health Science Center, Houston

Angela L Stotts, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas Health Science Center, Houston

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Texas Medical School- Houston, Dept. of Psychiatry Mental Sciences Institute

Houston, Texas, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Jessica Vincent, BS

Role: CONTACT

Phone: 713-486-2803

Email: [email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Rolanda Johnson, MA

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

P50DA009262

Identifier Type: NIH

Identifier Source: secondary_id

View Link

DPMCDA

Identifier Type: OTHER

Identifier Source: secondary_id

NIDA-09262-13

Identifier Type: -

Identifier Source: org_study_id