A New Radiation Therapy Planning System in Patients Undergoing Radiation Therapy for Cancer
NCT ID: NCT00436397
Last Updated: 2010-02-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
60 participants
INTERVENTIONAL
2002-06-30
2005-08-31
Brief Summary
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PURPOSE: This clinical trial is studying a new radiation therapy planning system in patients undergoing radiation therapy for extracranial cancer.
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Detailed Description
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* Determine the ability of the Radionics Body System™ to immobilize and re-localize patients receiving radiotherapy to extra-cranial sites of cancer.
* Determine the accuracy of radiation dose calculations for extra-cranial sites of cancer when using the XPLAN™-intensity modulated radiation therapy (XPLAN™/IMRT) integrated software in this system.
OUTLINE: Patients receiving radiotherapy have a Body Localizer cast constructed and undergo a CT scan while immobilized in the Body Localizer. Patients undergo another CT scan in the treatment position using the standard alpha cradle. The XPLAN™-intensity modulated radiation therapy (XPLAN™/IMRT)-generated treatment plan is compared to the standard treatment plan to verify that the calculated dose is within 2-3 percent of the planned dose using standard technique. Patients undergo sets of CT scans 3 additional times over the next few weeks for a total of 8 CT scans Patients may undergo additional CT scans before and after radiotherapy treatments for a maximum of 5 CT scans per week performed over the course of radiotherapy.
PROJECTED ACCRUAL: Approximately 60 patients will be accrued for this study.
Conditions
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Study Design
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TREATMENT
Interventions
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radiation therapy
Eligibility Criteria
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Exclusion Criteria
PATIENT CHARACTERISTICS:
Age
* Not specified
Performance status
* Not specified
Life expectancy
* Not specified
Hematopoietic
* Not specified
Hepatic
* Not specified
Renal
* Not specified
Cardiovascular
* No right heart insufficiency
Other
* Not pregnant or nursing
* Fertile patients must use effective contraception
* Weight must not exceed 150 kilograms (330 pounds)
PRIOR CONCURRENT THERAPY:
Biologic therapy
* Not specified
Chemotherapy
* Not specified
Endocrine therapy
* Not specified
Radiotherapy
* See Disease Characteristics
Surgery
* Not specified
ALL
No
Sponsors
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National Cancer Institute (NCI)
NIH
Fox Chase Cancer Center
OTHER
Principal Investigators
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Steven Seigenberg, MD
Role: STUDY_CHAIR
Fox Chase Cancer Center
Locations
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Fox Chase Cancer Center - Philadelphia
Philadelphia, Pennsylvania, United States
Countries
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Other Identifiers
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FCCC-02604
Identifier Type: -
Identifier Source: secondary_id
CDR0000304713
Identifier Type: -
Identifier Source: org_study_id
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