Social Phobia Intervention Study of Mannheim

NCT ID: NCT00434759

Last Updated: 2012-11-28

Study Results

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

89 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-09-30

Study Completion Date

2011-12-31

Brief Summary

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Primary objective:

The purpose of this study is to examine efficacy and efficiency of a Stepped Care Program (SCP) for patients with Social Phobia in comparison to the standard cognitive therapy for Social Phobia according to D.M. Clark.

Secondary objective:

Further, it is intended to identify mechanisms of change which mediate treatment outcome and to identify differential predictors for therapy success for the two treatment conditions.

Detailed Description

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With prevalence rates (lifetime) up to 13% in western countries, Social Phobia is one of the most frequent mental disorders. Main objective of this clinical trial is the evaluation of the efficacy and efficiency of a stepped care program for patients with Social Phobia (SCP) as compared to a standard therapy (ST) for patients with social phobia. Both interventions are based on the cognitive therapy according to D.M. Clark.

The SCP starts with a 8-sessions self-help-module with minimal therapist contact via email. Patients who do not reach remission after this first step, enter step 2 which consists of 8 therapy sessions guided by a therapist. If patients are not remitted after that, they receive another 8 sessions of therapist-guided cognitive treatment in step 3. So the SCP contains 8, 16 or 24 sessions of therapy - depending on remission status of the patient. In contrast to that, the ST comprises 16 sessions of therapist-guided intervention.

The diagnostic status of the patients is assessed by blinded clinician raters before treatment, after every eighth therapy session, and at 5 follow-up timepoints in order to examine the stability of treatment effects (3, 6, 9, 12 and 30 months after the end of therapy). Besides efficacy and efficiency of the SCP vs. ST, mechanisms of change and differential predictors for therapy outcome will be investigated.

Hypotheses: We expect that

1. the SCP is significantly more effective than the ST.
2. the SCP is significantly more efficient than the ST.
3. the results referring to the efficacy will be stable up to 30 months after the end of treatment(Follow Up Phase).
4. the SCP will cause less primary and secondary costs than the ST.
5. successful therapy leads to an improvement in the following areas:

* reduction of biased information processing,
* reduction of negative thoughts, subjective anxiety, safety behaviors, self-focused attention and autonomic arousal in anxiety-provoking situations,
* amelioration of verbal and non-verbal social competence in anxiety- provoking situations.

As mediators of change, the factors maintaining social anxiety according to the model of Social Phobia by Clark and Wells (1995) will be investigated.

Conditions

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Social Phobia

Keywords

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randomized controlled trial stepped-care program cognitive therapy of social phobia according to D.M. Clark

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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SCP

SCP is a stepped-care program with a self-help module with minimal therapist contact (8 sessions) as first step, followed by therapist-guided intervention depending on status of remission (8 sessions up to a maximum of 16 sessions).

Group Type ACTIVE_COMPARATOR

stepped care program based on cognitive therapy

Intervention Type BEHAVIORAL

starting with a digital-video-disk-based (DVD-based) self-help module (8 Sessions) followed by face-to-face-therapy including 8 or 16 sessions depending on remission status; including: changing safety behaviors, self-focused attention, and automatic negative thoughts in anxiety-provoking situations via cognitive techniques, for example role plays and behavioral experiments

ST

A standard therapy which means a therapist-guided intervention with 16 sessions face-to-face therapy.

Group Type ACTIVE_COMPARATOR

cognitive therapy

Intervention Type BEHAVIORAL

changing safety behaviors, self-focused attention, and automatic negative thoughts in anxiety-provoking situations via cognitive techniques, for example role plays and behavioral experiments

Interventions

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cognitive therapy

changing safety behaviors, self-focused attention, and automatic negative thoughts in anxiety-provoking situations via cognitive techniques, for example role plays and behavioral experiments

Intervention Type BEHAVIORAL

stepped care program based on cognitive therapy

starting with a digital-video-disk-based (DVD-based) self-help module (8 Sessions) followed by face-to-face-therapy including 8 or 16 sessions depending on remission status; including: changing safety behaviors, self-focused attention, and automatic negative thoughts in anxiety-provoking situations via cognitive techniques, for example role plays and behavioral experiments

Intervention Type BEHAVIORAL

Other Intervention Names

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cognitive therapy of social phobia according to D.M. Clark based on cognitive therapy for social phobie by Clark & Wells (1995)

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of Social Phobia according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV)
* Duration of the disorder at least 1 year
* Severity of symptomatology according to at least one of two self-report measures for social anxiety above Cut-Off: Social Interaction Anxiety Scale (SIAS: value of 26 or more) and / or Social Phobia Scale (SPS: value of 17 or more)
* Age: 18-60
* Written Informed Consent

Exclusion Criteria

* Social Phobia is not the main diagnosis
* Mental Retardation
* Lifetime Diagnoses: Schizophreniform Disorder, Bipolar Affective Disorder
* Acute Diagnoses: severe Major Depression Episode, severe Anorexia Nervosa, Substance-, Drug - or Alcohol-Dependence, life-threatening suicidal crisis
* Psychotropic medication (except stable treatment with antidepressant since 3 months before study start: medication and dosage has to be stable during the entire study duration)
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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German Research Foundation

OTHER

Sponsor Role collaborator

Central Institute of Mental Health, Mannheim

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Martin Bohus, MD

Role: STUDY_DIRECTOR

Central Institute of Mental Health in Mannheim

Locations

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Central Institute of Mental Health

Mannheim, Baden-Wurttemberg, Germany

Site Status

Countries

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Germany

Other Identifiers

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SP-32000

Identifier Type: -

Identifier Source: org_study_id