Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards

NCT ID: NCT00431483

Last Updated: 2013-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

779 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-02-28

Study Completion Date

2008-02-29

Brief Summary

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The purpose of this study is to establish the impact of a pharmacist's recommendations regarding choice, dosing and duration of antibiotic therapy on quality and cost of antibiotic treatment on surgical wards.

Detailed Description

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Inappropriate or incorrect use of antibacterials exerts selection pressure on pathogens potentiating emergence of resistance, puts patients at risk for unnecessary adverse drug reactions and potentially prolongs the length of stay in hospital thus increasing healthcare costs.

In an effort to improve the quality of antibiotic drug therapy on surgical wards of a large university hospital, specific consulting by a clinical pharmacist was established.

The objective of this study is to assess the impact of pharmaceutical consulting on the quality and costs of antibiotic use in surgical wards.

Comparison:

Within a control period the current pattern of antibiotic use is monitored. During the intervention period, the impact of the interventions made by the clinical pharmacist on antibiotic use is examined. One ward serves as a parallel control group; no intervention is being made on this ward throughout this study.

Conditions

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Bacterial Infections

Keywords

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antibacterial agents surgery pharmacist economics, pharmaceutical

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Pharmaceutical counseling

Group Type OTHER

pharmaceutical consulting

Intervention Type BEHAVIORAL

to measure if information and advice by a pharmacist has an impact on quality and quantity of prescribed antibacterials

Interventions

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pharmaceutical consulting

to measure if information and advice by a pharmacist has an impact on quality and quantity of prescribed antibacterials

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* female and male patients receiving antibiotics for a proven or suspected infection on designated surgical wards

Exclusion Criteria

* patients under 18
* patients unable or unwilling to consent to their data being evaluated
* patients receiving antibiotics perioperatively as prophylaxis
* patients receiving antibiotics for less than 48hrs
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ludwig-Maximilians - University of Munich

OTHER

Sponsor Role lead

Responsible Party

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Alexandra Weber

Pharmacist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Karl-Walter Jauch, Prof. Dr.

Role: STUDY_DIRECTOR

Klinikum Grosshadern

Locations

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Luwig Maximilians University - Klinikum Grosshadern

Munich, Bavaria, Germany

Site Status

Countries

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Germany

Other Identifiers

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AW2007

Identifier Type: -

Identifier Source: org_study_id