Long-Term IOP Fluctuation and VF Progression After Triple Procedure

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-10-31

Study Completion Date

2005-12-31

Brief Summary

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Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for patients with coexisting glaucoma and visually significant cataracts.

Detailed Description

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Previous studies reported that lowering intraocular pressure (IOP) slowed the advancement of visual field damage in glaucoma patients. However, even if the IOP can been substantially lowered, reduction of mean and peak IOP does not always prevent visual field progression.We believe that the long-term IOP fluctuation may play a significant role in visual field deterioration in those patients.

Conditions

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Glaucoma Filtering Surgery Intraocular Pressure

Study Design

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Observational Model Type

DEFINED_POPULATION

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Underwent triple procedure
2. At leas 3 years of follow-up after surgery
3. IOP \<18mmHg at each postoperative visit
4. A minimum of 5 visual field examinations
5. A reference visual field defect score of 16 or less
6. Good reliability indices of visual field

Exclusion Criteria

1. Any other significant ocular diseases or intraocular surgical histories,
2. Diseases that may affect visual field or diabetes

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Principal Investigators

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Gong Je Seong, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Yondgong Severance Hospital, Yonsei University College of Medicine

Locations

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Yonsei University College of Medicine

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Hong S, Seong GJ, Hong YJ. Long-term intraocular pressure fluctuation and progressive visual field deterioration in patients with glaucoma and low intraocular pressures after a triple procedure. Arch Ophthalmol. 2007 Aug;125(8):1010-3. doi: 10.1001/archopht.125.8.1010.

Reference Type DERIVED

PMID: 17698746 (View on PubMed)

Other Identifiers

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3-2006-0388

Identifier Type: -

Identifier Source: org_study_id