Heredity of Retinal Vessel Tortuosity

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

218 participants

Study Classification

OBSERVATIONAL

Study Start Date

1998-01-31

Study Completion Date

1998-12-31

Brief Summary

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The purpose of this study is to asses the relative influence of genetic and environmental influence on the tortuosity of retinal arterioles in eyes of 218 healthy Danish twins aged 20-46 years. We expect to find a high heredity for the variation in tortuosity. This knowledge can contribute to the elucidation of the pathology in retinal diseases.

Detailed Description

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All persons underwent an ophthalmic examination including refraction, slit lamp biomicroscopy and digital fundus photography. Two independent graders (both with an MD degree) made a visual grading of the severity of tortuosity of the retinal arterioles in the fundus images.

Conditions

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Retinopathy of Prematurity

Keywords

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retinal vessels tortuosity

Study Design

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Observational Model Type

DEFINED_POPULATION

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

* Samesex twin pairs of self-assessed good health

Exclusion Criteria

* Diabetes mellitus
* Hypertension
* Thyroid disease
* Cataract or other opacities of the refractive media
* Missing fundus photographs

Minimum Eligible Age

20 Years

Maximum Eligible Age

46 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Principal Investigators

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Michael Larsen, Prof. MD

Role: PRINCIPAL_INVESTIGATOR

Department of Ophthalmology Glostrup Hospital University of Copenhagen

Locations

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Department of Ophthalmology Glostrup Hospital

Glostrup Municipality, Copenhagen County, Denmark

Site Status

Countries

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Denmark

Other Identifiers

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Danish Twin Registry 1998

Identifier Type: -

Identifier Source: org_study_id