The Effect of MK 0633 in Patients With Atherosclerosis (0633-008)(COMPLETED)

NCT ID: NCT00421278

Last Updated: 2016-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-11-30

Study Completion Date

2007-01-31

Brief Summary

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A study to test the effects of study drug (MK 0633) on patients with Atherosclerotic disease

Detailed Description

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Conditions

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Atherosclerosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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1

Arm 1: Drug

Group Type EXPERIMENTAL

MK0633

Intervention Type DRUG

Single dose MK0633 100mg po in the fed state administered during a 4-wk study.

Interventions

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MK0633

Single dose MK0633 100mg po in the fed state administered during a 4-wk study.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients with plaque in coronary or leg arteries, known as atherosclerosis or peripheral vascular disease
* Inflammatory marker found in your blood, known as hsCRP \> 0.5 mg/L

Exclusion Criteria

* Age \< 40 or \> 85
* Female
* Heart attack, coronary artery bypass, stroke or unstable angina in last 3 months
* Liver diseased or abnormalities
* HIV infection
* Lupus, rheumatoid arthritis, cancer \<5 years
Minimum Eligible Age

40 Years

Maximum Eligible Age

85 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Merck Sharp & Dohme LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Medical Monitor

Role: STUDY_DIRECTOR

Merck Sharp & Dohme LLC

Other Identifiers

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MK0633-008

Identifier Type: -

Identifier Source: secondary_id

2006_563

Identifier Type: -

Identifier Source: secondary_id

0633-008

Identifier Type: -

Identifier Source: org_study_id

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