Hypercoagulability and Thromboembolic Risk in Patients With Malignant Disease, Evaluated by Thrombelastograph (TEG®)
NCT ID: NCT00400504
Last Updated: 2006-11-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
500 participants
OBSERVATIONAL
2006-11-30
Brief Summary
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Conventional haemostatic tests are not suitable as a screening tool of a hypercoagulable state. A hypercoagulable profile identified with the whole blood Thrombelastograph (TEG) Analyzer parameter maximal amplitude (MA) is reported to correlate with thrombotic events in patients undergoing major non-cardial surgery and recurrent ischemic events in patients undergoing percutaneous coronary intervention.
In this study we investigate the correlation between TEG measurements and thromboembolic events in patients with newly diagnosed malignancies.
The hypotheses of this study are:
1. Patients with malignancies and hypercoagulability, defined as a TEG MA\>69 mm and /or R\<4 min is at increased risk of developing thromboembolic complications as compared to those with a MA\<69 mm and/or a R\>4 min.
2. Hypercoagulability and hence TEG R and MA values are affected by the treatment instituted in these patients (chemo and radiation therapy) rendering the patients more hypercoagulable and hence at increased risk of developing thrombotic complications.
Detailed Description
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Conditions
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Keywords
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Study Design
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DEFINED_POPULATION
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Rigshospitalet, Denmark
OTHER
Principal Investigators
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Pär I Johansson, MD
Role: STUDY_CHAIR
Rigshospitalet, Denmark
Gedske Daugaard, MD
Role: STUDY_DIRECTOR
Rigshospitalet, Denmark
Locations
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Rigshospitalet
Copenhagen, Copenhagen, Denmark
Countries
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Central Contacts
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Other Identifiers
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TEG-Onkologi
Identifier Type: -
Identifier Source: org_study_id