Whole Body Vibration - a New Therapeutic Approach to Improve Muscle Function in CF

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-06-30

Study Completion Date

2006-08-31

Brief Summary

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The purpose of this study is to evaluate the effects of whole body vibration (WBV) on muscle function in adult CF-patients.

Detailed Description

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Cystic Fibrosis (CF) is the most common chronic hereditary disease in Caucasians. Due to improved therapy and better understanding of the disease, life expectancy has risen to an average of 38 years and is continuing to rise. With the increased life-expectancy it becomes even more important to maintain functional activity as part of quality of life. Mechanical stimulation in form of whole body vibration (WBV) is a new type of exercise currently tested in sports, geriatrics and rehabilitation. It has recently been found to be a safe and efficient method to activate muscular activity via stretch reflexes leading to improvement of muscular performance, body balance and physical functioning.

10 patients of the CF Center Cologne, Germany, took part in the Galileo study. They were provided by the vibrating platform (Galileo 2000)for whole body vibration training at home. The patients were standing in an upright position receiving vertical vibration of frequencies between 20-25 Hz. This vibration exercise evokes muscle contractions via stretch reflexes improving muscular activity. The training schedule consisted of three 3-minute sessions twice a day 5 days per week for 3 months.

Every 4 weeks the patients were seen for assessment of muscle function to evaluate the effects of this new intervention.

Conditions

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Cystic Fibrosis

Keywords

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whole body vibration muscle function cystic fibrosis mechanography chair-rising-test

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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GALILEO

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* clinical diagnosis of Cystic Fibrosis
* age older than 18 years

Exclusion Criteria

* hypersplenic syndrome
* acute arthritis or osteomyelitis

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Principal Investigators

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Eckhard Schoenau, Prof.

Role: STUDY_CHAIR

University Children´s Hospital Cologne, Germany

Locations

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CF Center Cologne, University Children's Hospital

Cologne, , Germany

Site Status

Countries

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Germany

References

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Fricke O, Weidler J, Tutlewski B, Schoenau E. Mechanography--a new device for the assessment of muscle function in pediatrics. Pediatr Res. 2006 Jan;59(1):46-9. doi: 10.1203/01.pdr.0000191580.07644.1c. Epub 2005 Dec 2.

Reference Type BACKGROUND

PMID: 16327004 (View on PubMed)

Other Identifiers

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05-005

Identifier Type: -

Identifier Source: org_study_id