Trial Outcomes & Findings for Effect of Prolonged Electrical Stimulation on Neural Plasticity in Spinal Cord Injury (NCT NCT00387673)

NCT ID: NCT00387673

Last Updated: 2017-06-16

Results Overview

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

11 participants

Primary outcome timeframe

Outcome measures: baseline, 6 weeks after baseline, post testing, 6 weeks post testing

Results posted on

2017-06-16

Participant Flow

Participant milestones

Participant milestones
Measure
Arm 1
6 weeks of upper extremity training for 3 sessions/week, as follows: a) somatosensory stimulation of the median, ulnar and radial nerves at the level of the wrist (2 hours/session); Somatosensory Stimulation and Massed Practice Training: a) somatosensory stimulation of the median, ulnar and radial nerves at the level of the wrist (2 hours/session); SS group b) somatosensory stimulation of the median, ulnar and radial nerves at the wrist (2 hours/session) followed by an activity-based upper extremity training program (1 hour/session); SS+ABT group and c) sham somatosensory stimulation of the median, ulnar and radial nerves at the wrist (2 hours/session) followed by an activity-based upper extremity training program (1 hour/session); ABT group then carry out training in the 3 subject groups simultaneously, each group consisting of 2 subjects at a time, with 2 sets of subjects/year over a 2-year period, yielding a target sample of 36 subjects.
Arm 2
a 6-week period of 2 hours somatosensory stimulation of the hand, without training Somatosensory Stimulation and Massed Practice Training: a) somatosensory stimulation of the median, ulnar and radial nerves at the level of the wrist (2 hours/session); SS group b) somatosensory stimulation of the median, ulnar and radial nerves at the wrist (2 hours/session) followed by an activity-based upper extremity training program (1 hour/session); SS+ABT group and c) sham somatosensory stimulation of the median, ulnar and radial nerves at the wrist (2 hours/session) followed by an activity-based upper extremity training program (1 hour/session); ABT group then carry out training in the 3 subject groups simultaneously, each group consisting of 2 subjects at a time, with 2 sets of subjects/year over a 2-year period, yielding a target sample of 36 subjects.
Arm 3
a 6-week period of 2 hours sham somatosensory stimulation of the hand, followed by 1 hour of activity-based training Somatosensory Stimulation and Massed Practice Training: a) somatosensory stimulation of the median, ulnar and radial nerves at the level of the wrist (2 hours/session); SS group b) somatosensory stimulation of the median, ulnar and radial nerves at the wrist (2 hours/session) followed by an activity-based upper extremity training program (1 hour/session); SS+ABT group and c) sham somatosensory stimulation of the median, ulnar and radial nerves at the wrist (2 hours/session) followed by an activity-based upper extremity training program (1 hour/session); ABT group then carry out training in the 3 subject groups simultaneously, each group consisting of 2 subjects at a time, with 2 sets of subjects/year over a 2-year period, yielding a target sample of 36 subjects.
Overall Study
STARTED
0
0
0
Overall Study
COMPLETED
0
0
0
Overall Study
NOT COMPLETED
0
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Effect of Prolonged Electrical Stimulation on Neural Plasticity in Spinal Cord Injury

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Effect of Prolonged Electrical Stimulation on Neural Plastici
Sex: Female, Male
Female
0
n=5 Participants
Sex: Female, Male
Male
0
n=5 Participants

PRIMARY outcome

Timeframe: Outcome measures: baseline, 6 weeks after baseline, post testing, 6 weeks post testing

Population: Project has officially closed. PI for this project has left VA without forwarding information.

Outcome measures

Outcome data not reported

Adverse Events

Project Closed

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kristina Beekhuizen

Miami VA Healthcare System

Phone: 305-575-7000

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place