Exercise and Bright Light Treatment: Effects on Body Weight and Composition

NCT ID: NCT00384345

Last Updated: 2006-10-06

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE2
• Total Enrollment: 24 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2003-09-30
• Study Completion Date: 2003-12-31

Brief Summary

Bright light therapy has been used to safely and effectively treat conditions such as Seasonal Affective Disorder and to regularize sleep in patients with circadian rhythm disorder. Based on evidence of the link between bright light, serotonin, mood and carbohydrate metabolism, it has been suggested that bright light therapy can improve weight loss but the literature on the subject is sparse. Further, the literature suggests that apart from any changes in mood and carbohydrate metabolism, bright light may reduce the unpleasant side-effects of exercise and increase compliance to an exercise program.

Detailed Description

Objective: Increased physical activity is important given the concern over the growing rates of obesity. Bright light therapy has the potential to enhancing serotonin levels, impact on carbohydrate metabolism and reducing soreness and hyperthermia associated with physical activity. The aim of this study is to conduct a controlled investigation of the effects of bright light therapy and exercise on weight loss and body composition in overweight individuals.

Research Methods and Procedures: Twenty-five overweight male and female subjects will be assigned to 6 weeks of moderate exercise with or without bright light treatment. Outcome measure included changes in body mass and body composition and ratings of mood, seasonality and sleep.

Conditions

Obesity; Fatigue

Keywords

bright light treatment; exercise; body fat index; mood; sleep; fatigue

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Interventions

Bright Light Therapy

Intervention Type: DEVICE

Exercise

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Overweight subjects
• Subjects in otherwise good health
• Subjects willing to participate in a 6-week moderate exercise program
• Bedtime between 10pm and 12am; wake-up time between 6am and 8am
• Score in the median range of the Morningness/ Eveningness Questionnaire (i.e., subjects show no distinct characteristics of phase delay or phase advance)

Exclusion Criteria

• Progressive eye disease
• History of cataracts, macular degeneration or have undergone laser corrective eye surgery in the past 30 days.
• Currently taking any medications, e.g. antibiotics, tricyclic antidepressants, that may affect photosensitivity
• History of heart disease
• History of respiratory diseases, such as asthma, emphysema
• Any severe or uncontrolled general medical condition
• Severe psychiatric disorder (as determined by psychiatrist - CMS)
• History of mania
• Grossly obese individuals with morbid obesity

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 55 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

The Litebook Company Ltd.

INDUSTRY

Sponsor Role: collaborator

University Health Network, Toronto

OTHER

Sponsor Role: lead

Principal Investigators

Colin M. Shapiro, MBBCh, PhD

Role: PRINCIPAL_INVESTIGATOR

University Health Network, Toronto

Locations

University Health Network

Toronto, Ontario, Canada

Countries

Canada

Other Identifiers

03-0184-BE

Identifier Type: -

Identifier Source: org_study_id