Trial Outcomes & Findings for Comparison of Bystander Fatigue and CPR Quality When Using Two Different CPR Ratios. (NCT NCT00380757)

Results Overview

Number of adequate chest compressions per minute

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

42 participants

Primary outcome timeframe

over a 5 minute period

Results posted on

2025-04-15

Participant Flow

Participant milestones

Participant milestones
Measure	CPR 30:2 First Then 15:2 30 chest compressions to 2 ventilations bystander CPR using 30:2 ratio for a 5-minute period. After a 5-minute rest period, the participants will administer bystander CPR using a 15:2 ratio for 5 minutes	CPR 15:2 First Then 30:2 15 chest compressions to 2 ventilations bystander CPR using 15:2 ratio for 5 minutes, followed by a 5-minute rest period. Then participants assigned to this group will administer bystander CPR using 30:2 ratio for 5 minutes.
Sequence 1 (First Assigned CPR Ratio) STARTED	21	21
Sequence 1 (First Assigned CPR Ratio) COMPLETED	21	21
Sequence 1 (First Assigned CPR Ratio) NOT COMPLETED	0	0
Sequence 2 (Second Assigned CPR Ratio) STARTED	21	21
Sequence 2 (Second Assigned CPR Ratio) COMPLETED	21	21
Sequence 2 (Second Assigned CPR Ratio) NOT COMPLETED	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Comparison of Bystander Fatigue and CPR Quality When Using Two Different CPR Ratios.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	CPR 30:2 n=21 Participants 30 chest compressions to 2 ventilations bystander CPR using 30:2 ratio vs 15:2 ratio: Participants will use 2 CPR techniques with different chest compression to ventilation ratios	CPR 15:2 n=21 Participants 15 chest compressions to 2 ventilations bystander CPR using 30:2 ratio vs 15:2 ratio: Participants will use 2 CPR techniques with different chest compression to ventilation ratios	Total n=42 Participants Total of all reporting groups
Age, Continuous	66.4 years STANDARD_DEVIATION 8.7 • n=5 Participants	65.6 years STANDARD_DEVIATION 7.1 • n=7 Participants	66.0 years STANDARD_DEVIATION 7.9 • n=5 Participants
Sex: Female, Male Female	17 Participants n=5 Participants	12 Participants n=7 Participants	29 Participants n=5 Participants
Sex: Female, Male Male	4 Participants n=5 Participants	9 Participants n=7 Participants	13 Participants n=5 Participants
Region of Enrollment Canada	21 participants n=5 Participants	21 participants n=7 Participants	42 participants n=5 Participants

PRIMARY outcome

Timeframe: over a 5 minute period

Population: Two recordings were later determined to be technically inadequate. Results are only reported for the CPR sequence that the participant was assigned to start with.

Number of adequate chest compressions per minute

Outcome measures

Outcome measures
Measure	CPR 30:2 n=19 Participants 30 chest compressions to 2 ventilations	CPR 15:2 n=19 Participants 15 chest compressions to 2 ventilations
CPR Quality	128.5 count of chest compressions Standard Deviation 130.4	126.6 count of chest compressions Standard Deviation 129.9

SECONDARY outcome

Timeframe: After 5 minutes of 15:2 CPR or 30:2 CPR

Measures of bystander fatigue measured using the Borg's Scale for Rating of Perceived Exertion (range 6-20) measured at baseline, following first CPR sequence, before beginning second sequence and at end of second CPR sequence. Lower values represent light perceived exertion, and higher values represent higher perceived exertion. Values reported are the difference between the baseline Borg Scale measured before beginning each CPR sequence and the Borg Scale following 5 minutes of each CPR sequence.

Outcome measures

Outcome measures
Measure	CPR 30:2 n=42 Participants 30 chest compressions to 2 ventilations	CPR 15:2 n=42 Participants 15 chest compressions to 2 ventilations
Borg Rating of Perceived Exertion Blood Pressure Borg Rating of Perceived Exertion Scale	3.3 units on a scale Standard Deviation 2.2	3.5 units on a scale Standard Deviation 1.9

Adverse Events

CPR 15:2

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

CPR 30:2

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Manya Charette

Ottawa Hospital Research Institute

Phone: 613-798-5555

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place