Study of Improving Insulin Sensitivity by Electroacupuncture Therapy
NCT ID: NCT00379379
Last Updated: 2006-09-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
26 participants
INTERVENTIONAL
2005-01-31
2005-12-31
Brief Summary
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Detailed Description
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We undertook a randomized, single blind and sham group controlled study to evaluate the effect of EA with a frequency in 15 Hz and fixed intensity (10 mA) on human Zusanli acupoint. A total of 26 newly diagnostic type II diabetic patients are enrolled in this study. They are randomly divided into 2 groups. There are 13 patients in the experimental group (EG) with EA treatment, and the other 13 patients are divided into control group (CG) with sham treatment. The main outcome is the changes of laboratory parameters between before and 30 minutes after the test.
Conditions
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Keywords
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Study Design
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RANDOMIZED
FACTORIAL
TREATMENT
SINGLE
Interventions
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electroacupuncture
Eligibility Criteria
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Inclusion Criteria
* age between 30 to 65 years old
* controlled BP below 140/90 mmHg
* oral hypoglycemic agent (OHA) therapy with Gliclazide twice per day.
Exclusion Criteria
* patient had received insulin therapy
* severe disease such as CVA, CAD within 6 months
* Arrhythmia history and on pacemaker.
30 Years
65 Years
ALL
No
Sponsors
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China Medical University, China
OTHER
China Medical University Hospital
OTHER
Principal Investigators
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Shih-Liang Chang, M.D., Ph.D.
Role: PRINCIPAL_INVESTIGATOR
Graduate Institude of Integration Chinese and Western Medicine, China Medical University
Locations
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Graduate Insititude of Integration Chinese And Western Medicine, China Medical University
Taichung, , Taiwan
Countries
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References
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Chang SL, Lin JG, Chi TC, Liu IM, Cheng JT. An insulin-dependent hypoglycaemia induced by electroacupuncture at the Zhongwan (CV12) acupoint in diabetic rats. Diabetologia. 1999 Feb;42(2):250-5. doi: 10.1007/s001250051146.
Lin JG, Chang SL, Cheng JT. Release of beta-endorphin from adrenal gland to lower plasma glucose by the electroacupuncture at Zhongwan acupoint in rats. Neurosci Lett. 2002 Jun 21;326(1):17-20. doi: 10.1016/s0304-3940(02)00331-2.
Lin JG, Chen WC, Hsieh CL, Tsai CC, Cheng YW, Cheng JT, Chang SL. Multiple sources of endogenous opioid peptide involved in the hypoglycemic response to 15 Hz electroacupuncture at the Zhongwan acupoint in rats. Neurosci Lett. 2004 Aug 5;366(1):39-42. doi: 10.1016/j.neulet.2004.05.003.
Chang SL, Tsai CC, Lin JG, Hsieh CL, Lin RT, Cheng JT. Involvement of serotonin in the hypoglycemic response to 2 Hz electroacupuncture of zusanli acupoint (ST36) in rats. Neurosci Lett. 2005 Apr 29;379(1):69-73. doi: 10.1016/j.neulet.2004.12.057. Epub 2005 Jan 20.
Chang SL, Lin KJ, Lin RT, Hung PH, Lin JG, Cheng JT. Enhanced insulin sensitivity using electroacupuncture on bilateral Zusanli acupoints (ST 36) in rats. Life Sci. 2006 Aug 1;79(10):967-71. doi: 10.1016/j.lfs.2006.05.005. Epub 2006 May 17.
Other Identifiers
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DMR93-IRB-127
Identifier Type: -
Identifier Source: org_study_id